ID A0A1S3T1R9_SALSA Unreviewed; 1698 AA.
AC A0A1S3T1R9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 1-like isoform X9 {ECO:0000313|RefSeq:XP_014070538.1};
GN Name=LOC106613115 {ECO:0000313|RefSeq:XP_014070538.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014070538.1};
RN [1] {ECO:0000313|RefSeq:XP_014070538.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014070538.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR RefSeq; XP_014070538.1; XM_014215063.1.
DR STRING; 8030.ENSSSAP00000048519; -.
DR PaxDb; 8030-ENSSSAP00000048519; -.
DR GeneID; 106613115; -.
DR OrthoDB; 92033at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF10; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|RefSeq:XP_014070538.1};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_014070538.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 1335..1457
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1531..1697
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 727..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1170..1335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..50
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..380
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1115..1147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1199..1231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1232..1292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1317
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1698 AA; 186733 MW; 5B3C60CDBDFF0D79 CRC64;
MNKAPQSITR PHPAPSPGLQ LPTFPPGQPP SVVFATPPPQ MNPAPQPRQF APVPRALHQQ
SYYSRPSLPS NAPRMPPSST PRPVAPTHVY QPGQQMMMMI PSQQIPFPNQ QGPAYFIPGQ
YRSTYVATPQ QYPVPPGTPG FYPGTSPAEY GTYAGAYYPA QQQYTPSVPA APVIMNPPSQ
QQQLPPQQQI QPKRERKQVQ IIIRDPNQGG KDITEEIMSG GTRSGSTPTP PQVSDDSSES
SGSEGPAVAQ ANGENTTPVV VRPDDRGKPA ATLITGPPAL SKTPELVKTA PTEVKLPDTD
SKSPSLPQDL PTPPRVTTTL HTTAPGTTPP STSPIADMMD APAPAAAPAP TAAPAPTAAP
ALSAPKVPAY PAPLLEPRPT PAAEEQPSAA KEAREEVKEK EEMEAREVTT SSKPEPSLAP
VTNPSSGTNG VSATQPLPEE EPAALSITMP SPQAAEPPLD FPIAQPEELR LPNGLPLPSP
QDPEKVSAES SECDLSPFAE PEVAPLQREA PAPVAATATP DPVVQATVAP VVLAETASTT
EVTPRQMEDE MDSPPSQRTT PAGENSMQAA VSVPKKKRKM KDLNRKEAVG DLLDAFKEEQ
VVQSPPEQAT PTSASDAEEP RPAATPAVAE VDETWEEKED KLDAENIEPK PGDLKYQYKE
ELCRPIDPEE KKRYDRDFLL GFQFISAAMS KPEGLPQISD VVLDTANKAP LRQLDPSRLP
GMNMGPDFTP SFANLGRPGM GGGGGHRGGP PSGMSGGGPR RSQQGQRKEP RRIINISSSL
TDDVKLNKAE DAWKPAVKKA ASGQAAPEEE SDDPEQAKTQ ELFKRVRSIL NKLTPQMFQQ
LMKQVKELTI DTEERLKGVI DLIFEKAISE PNFSVAYANM CRCLMGLKVP TTDKPGVTVN
FRKLLLNRCQ KEFEKDKDDD VIFDKKQKEL DAAAMEEKDR LKAELEEAKD MARRRSLGNI
KFIGELFKLK MLTEAIMHDC IVKLLKNHDE ESLECLCRLL STIGKDLDFE KAKPRMDQYF
VQMDKIIKEK KTSSRIRFML QDVLDLRRNT WVPRRGEQGP KTIDQIHKDA ELEEHREVLK
VQQQLLNQNT RGGGGGRGGG GGGGGGGRDQ GNRGGQHPQA GQRSQPQDED WNTVPISTKS
RPIDTSRLSK ITKPGALDFN NQLLAPQLGG KGMWGSWGKG SSGGTTGAKP AGEATPESGG
RPATSTLNRF SALQPQQPSS SGPSQDSDRR VPLRNSSSRD RGSDRFERHD RGSNDRFDRR
DDRNRPPVTK RSFSRETKEH SREREHRGPS DPIRRVASMT DDPGSRDRAR SKENVKREAV
ATPPTQTKPS LSEEELEKKT TAIIEEYLHI NDMKEALQCV VEMNSTRLLF VFVRSGLEST
LERSPIARER TGLLLHQLYK AGTLPTEQYY RGLQEILEVA EDMAIDIPHI WLYLAELITP
MLHEGGIPMG PLFKEISKPL VPQGTAGVLL VQILTLLCRG MSRKKAGAMW REAGLSWKDF
LPEDEDVNKF VTEKNVEFTL GGGGDDETEK SSKKELSSEE LNKQLDRLIQ DKADNQRIYD
WVEANLDETQ ISSNVFVRAV MTAICQSAIL CENPYKLDAK VITRRARLLH KYLKDEQKEL
QALYALQALM VEMEQPANLL RMFFDTLYDE DVIKEEAFYK WESSKDPAEM QGKGVALKSV
TAFFTWLREA EDEESDNS
//
