ID A0A1S3T272_SALSA Unreviewed; 1562 AA.
AC A0A1S3T272;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Roundabout homolog 2-like isoform X11 {ECO:0000313|RefSeq:XP_014070692.1};
GN Name=LOC106613191 {ECO:0000313|RefSeq:XP_014070692.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014070692.1};
RN [1] {ECO:0000313|RefSeq:XP_014070692.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014070692.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014070692.1; XM_014215217.1.
DR PaxDb; 8030-ENSSSAP00000070704; -.
DR GeneID; 106613191; -.
DR OrthoDB; 5396194at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR CDD; cd07693; IgC_1_Robo; 1.
DR CDD; cd05726; IgI_4_Robo; 1.
DR CDD; cd20952; IgI_5_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF52; ROUNDABOUT HOMOLOG 2; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..1562
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010284641"
FT TRANSMEM 891..913
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..148
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 154..241
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 246..333
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 342..437
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 445..526
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 553..647
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 666..764
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 768..865
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 32..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1160..1188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1247..1323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1348..1562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1247..1265
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1280..1297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1361..1378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1461..1496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1511..1527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1562 AA; 170216 MW; 82F877B6BADD4E72 CRC64;
MFSMAKFGFF SIFELVLFLL VLFGGPELSH QARTKGRWNK GGSRLRQEDS PPRIVEHPSD
LIVSKGEPAT LNCKAEGRPS PTVEWYKDGE RVETDKDDPR SHRMLLPSGS LFFLRIVHGR
RSKPDEGSYV CVARNYLGEA ISHNASLEVA LLRDDFRQNP TDVVVAAGEP AILECIPPRG
HPEPTIYWKK DKVRIEDKED RITIRGGKLM ISNTRKSDAG MFICVGTNMV GERDSETAQL
TVFERPTFLR RPINQVVLEE EGVEFRCQVQ GDPQPNVRWR KNDVDVPRGR YEIKYDKEDY
LLRVKKASAS DEGTFTCLAE NRVGKVEASA SLTVRARPVA APQFIIRPRD QIVAQGRTAT
FPCETKGNPQ PAVFWQKEGS QNLLFPNQPQ QPNSRFSVSS SGDLTISSVQ RTDAGYYICQ
ALTVAGSILA KAQLEVTDVL TDRPPPIIRR GPSNQTLRVD SVALLKCQAS GDPIPSISWL
KDGVSLLGKD PRMSLQELGS LQMRSLRLSD SGIYTCVAAS SSGETSWSAF LEVKDQAGVM
VIKNRDDNEL PGPPSKPQVT DVTKNSVSLS WQPGLAGATP ISSFVIEAFS QSVSNSWQTV
ADHVKTTQYT VKGLRPNTIY LFMVRAVNTQ GLSDPSPMSE PVRTQDISPP AQGVDHRHVQ
KELGEVIVRL HNPVVLSPTT IQVTWTVDRQ SQFIQGYRVL YRQTSGMFSP GPWQTQDVKV
PSERSVVLSN LKKGIVYEIK VRPYFNEFQG MDSESRSART TEEAPSAPPL QVTVLTVGNQ
NSTSISISWD PPPPEHQNGI IQEYKIWCLG NETRFHVNKT VDAAIRSVVV GGLQVGVLYR
VEVAASTSAG VGVKSEPQPI VIGKDFRDVI ISGNRNNSIT EQITDVVKQP AFIAGIGGAC
WVILMGFSIW LYWRRKKRKG LSNYAVTFQR VDGGLMSNGS RPGLLNASDP GYPWLADSWP
ATSLPVNNGS GGPNDLSNFG RGDTSSNGDK TGTMLSDGAI YSSIDFTTKA NYNSPSQGSQ
GATPYATTQI LHSSSIHELA VDLPEAQWKA SIQAKQEMAN LGYSLPDKNS CNNSGKGGRK
KKAKVGTKPT KTNGSSWANV ALPPPPLHPL PGTEMDHYPN EHYEGGGYES DGWGPPMPVQ
TYLHQGMEDE LEEEEERVPT PPIRGVASSP AAVSFGQQST ATLSPSPREE LQPMLQAHLD
EITRAYQLDM AKQTWLMQGG SLPPLPPQAP APPVGYVSST LVSDLETDIP DEDEEDEEEE
EDEGYEMSRP LYGIEHTPGS SMDNLDSSVT GSMVNGWGSA SEEDDRHYSS HRSSVGSSSD
GSLYTHCSFA QALVAAADKA GYHLEGTSLA KRGKGLSHRP RPSSPFSTDG STVGTHSLGH
QRAARPTRKP RGQGTAPHRR DASADDLPPP PDPPPIQGPG YIQGARSVGG MGPPAERQAS
SLERQPMCGA MPLSGLEEMK SCMDRQTRTS LERHRQAQDR LASMDRGDDP RRGHKTEAGC
LPPYSKPSFP SPGGDISSGT ASSKGSTGPR KGEGPRGPHQ RAATDHSDFL GTNGPGHYAG
EL
//
