ID A0A1S3T2X7_SALSA Unreviewed; 2023 AA.
AC A0A1S3T2X7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Disks large homolog 5-like isoform X8 {ECO:0000313|RefSeq:XP_014070927.1};
GN Name=LOC106613304 {ECO:0000313|RefSeq:XP_014070927.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014070927.1};
RN [1] {ECO:0000313|RefSeq:XP_014070927.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014070927.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014070927.1; XM_014215452.1.
DR OrthoDB; 2877432at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR CDD; cd00992; PDZ_signaling; 4.
DR CDD; cd11860; SH3_DLG5; 1.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR006907; DLG5_N.
DR InterPro; IPR035537; DLG5_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR46360; DISKS LARGE HOMOLOG 5; 1.
DR PANTHER; PTHR46360:SF1; DISKS LARGE HOMOLOG 5; 1.
DR Pfam; PF16610; dbPDZ_assoc; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 4.
DR Pfam; PF04822; Takusan; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 4.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443}.
FT DOMAIN 1..92
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 701..791
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 786..877
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1446..1525
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1606..1687
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1843..2009
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 102..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 898..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1302..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 149..484
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 513..673
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 102..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1128..1143
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1159..1174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1182..1207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1233..1247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1302..1328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1336..1363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1380..1421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2023 AA; 227332 MW; BD13D84BD758462A CRC64;
MEPKHKELLE QFHQNLLDSI TDADRLIELL VISGTLSQLD RFELDQNCSS SAEKVDQLLK
MLVNKESDHF LELCVALEKA YPDLYSALFT NGGGPVDHSS GSTYSVLSTM PSDSESSSSL
SSVGSPPGNG SASSPPPAVN DNRPAGDNLD TILFQLRQVT RERDELRKRL ALASPGTTFD
DCRPNSKASH DYERLKSQCM RAMADLQSLQ NQHTKTLKRC EEAVKEADFY HMLHSRVLGD
QSQLKEELDV LRRDNTQLVR EHNHLKQSCE ELRRLHSEDQ KEVVDMRRQQ QEVMRENGSS
EVLNKLYDTA MDKLEGVRKE YDSLSKRYSE KVANHNTDLS RLEQVEEENR RLQKQMDTLL
RQRDTAIHYQ QQCSTSMRRF DSVQQELNKS SGQNKELQRE MERLQSEVTR CKNFQLKAVK
DCEKYKEERD SVFNEYRLIM SERDQVIKEL DKLQTELEAA EARLKNTSSE RMVASEEMEA
LRQELNSSLV DRDRAICERN ELLEKYCHEV KDKAEAQKEL SQACKDIETV REERDVARKE
RTEAIIQRDQ LLREYYQARQ KQDSATLDIE RANKEIEVLR KQYEAMSQEL KEATQEAEVA
KCRRDWAFQE RDKIVAERES IRTLCDNLRR ERDRAVSDLA DALRNLDDMR KQKNDASREL
KELKEKMESQ LDKEARFCQL MAHSSHDSAI DTDSLEWETE VVEFEKDRDD MDLKALGFDI
AEGVNDPYLP GDCGIFVTRV DKGSIADGRL RVNDWLLKIN DMDLTNKDRK QVVKAVLNRG
GLINMVVRRR KSLGGRLVTP VHINLIGHKD SGIGLENGVF VTALVQGSPA SREGSLTVGD
RLIAINGIAL DNKSVTECET LLRNCRDSLS LSLMKFFPHS SSGQNIFDSL RESSSNSRLS
EVHSRNSRNL KHNSSTQTDI FCPDTGGSVN VQGERRKSRG GEAEEGMGPY GDVRKPFSTG
SLHATSLRPS SDLGLGPPGR YGPSAFQECC SGSPYAKPPP PPMTYDPSNP PDCITVETTL
EKKHSGGTWP KMIVGGMSVA VDTTTATTPT QLSIFKSPKQ RKSIFDTDAF KPRPETAPPS
SKIEYLLPSQ LVAHSPQPSK TESLSSSSTA TPTPPPPPTR SDSFKFKHKQ QSNSASDCTL
TSDGNGGKGE AVSMVTGEGH GEQERERDRN GNHYFLDGKV LTSRKSCDED IGRTRGEEPE
VKRPRPKSAP ALRRRMTPQS ITLPSFQSYS NDDHSPEPRE MLRSSPNRSH RHSVGFVSTV
YNGTLPANSA HRGLAPCPAV TAVMRNPVYT VRSHRVHTNN CPSVSSQICQ HQHNNQHPSP
QHQGRLSLDL SQKRPAADYS ESSSRSSRTS HDSSSNVQYR NERIKIPSTP RYPRSMLGSD
RGSLSHSECS SPSLITPPQS PLNLETSSFA SSQSQSSIST LPRISVSPVP IGERRKDRPY
LEEPRNVIVQ KGAEPLGISI VSGENGGIFV SKVTGGSIAH QAGLEYGDQL LEYNGINLRN
ATEQQARLII GQQCDTITIM AQYNPHMYQL GNHSRSSSGL EPVSSQSTPQ GSGATTPDNH
STIDTLSEQD EGTLTPSSKQ TTPTTSPHSF IRMLSEGSRK VCEPRVVTVR RAQGAELGLG
LCGGNLRGVY VESLEEDSPA RGTEGLQPGD LILEYGSVNM KNKTVEEVYV EMLKPAETVT
FKVQQRQDDF NIVKDTPGDG FYIRALYERI VEAELDLSFK KDDILYVDDT LPKGSFGTWM
AWQLDENAQQ IQRGQIPSKY MMDQEFYRRH SMTELKDDKD SKSLSAAARR SFFRRKHKHK
RSGSKDGKEL VALDAISTDS IPFLEDCVSL AYQRVQKIEC ASPRPVLILG PLSDPVKDML
VKESPGKFCR CVLEVMKASQ QAIERGVKDC LFIDYKRRSG HFDVTTVASI KEITEKDCHC
LLDIAPHAIE RLHSVHIYPI VIFIRYKNSK QIKEQKDPVY LRDKVSQKHS KEQFEVAQKI
EQEYSKFFTG IVQGGTLPYI CTQIMTIVDQ EQSKVLWTPL GCS
//
