ID A0A1S3T450_SALSA Unreviewed; 437 AA.
AC A0A1S3T450;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=guanylate kinase {ECO:0000256|ARBA:ARBA00012961};
DE EC=2.7.4.8 {ECO:0000256|ARBA:ARBA00012961};
GN Name=LOC106613532 {ECO:0000313|RefSeq:XP_014071364.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014071364.1};
RN [1] {ECO:0000313|RefSeq:XP_014071364.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014071364.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the guanylate kinase family.
CC {ECO:0000256|ARBA:ARBA00005790}.
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DR RefSeq; XP_014071364.1; XM_014215889.1.
DR AlphaFoldDB; A0A1S3T450; -.
DR GeneID; 106613532; -.
DR KEGG; sasa:106613532; -.
DR OrthoDB; 324675at2759; -.
DR Proteomes; UP000087266; Chromosome ssa10.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004385; F:guanylate kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00071; GMPK; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR017665; Guanylate_kinase.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03263; guanyl_kin; 1.
DR PANTHER; PTHR23117:SF22; GUANYLATE KINASE 1; 1.
DR PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF00625; Guanylate_kin; 3.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00072; GuKc; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 4..186
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT DOMAIN 207..415
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 437 AA; 48582 MW; 5B139C1042057D5B CRC64;
MEGPRPVVLS GPSGAGKSTL MKMLLRDYDG VFGFSVSHTT RSPRPGEVDG KDYHFSNREA
MQEDIDDGTY IENAEFSGNL YGTSKSSVDE VRANGLICIL DVDIQGVRNI KQTDLDPIYV
SIQPPSMEIL EKRLRDRNTE TEESLQKRLE AARVDMELSN EPGVFDMLIV NDDLEEAYEK
LQSVLIEEIT KVQSTKKERC NSIMSGPRPV VISGPSGAGK STLLKKLLKD YKGVFGFSVS
HTTRDPRPGE VDGKGLFGLP MLLGATLLPV ADVLSSVSSA DYHFTNREAM QEDIDKGEFI
ETDEFSGNLY GTSKSAVQDV RAKGLICILD VDIAGVRHIK ETNLDPIYIS IQPPSIEVLE
ERLRGRATET EEKIQSRLEE ARTDMEECNE PGLFDIVIVN NDLDEAYEKL QSVLKEEMSD
VILMKAFQGQ TCYLISF
//
