ID   A0A1S3T6I3_SALSA        Unreviewed;       866 AA.
AC   A0A1S3T6I3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Neuroligin-1 isoform X1 {ECO:0000313|RefSeq:XP_014072202.1, ECO:0000313|RefSeq:XP_014072203.1};
GN   Name=nlgn1 {ECO:0000313|RefSeq:XP_014072202.1,
GN   ECO:0000313|RefSeq:XP_014072203.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014072202.1};
RN   [1] {ECO:0000313|RefSeq:XP_014072202.1, ECO:0000313|RefSeq:XP_014072203.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014072202.1,
RC   ECO:0000313|RefSeq:XP_014072203.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC       Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964}.
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DR   RefSeq; XP_014072202.1; XM_014216727.1.
DR   RefSeq; XP_014072203.1; XM_014216728.1.
DR   STRING; 8030.ENSSSAP00000091003; -.
DR   PaxDb; 8030-ENSSSAP00000091003; -.
DR   Ensembl; ENSSSAT00000203453; ENSSSAP00000142922; ENSSSAG00000116812.
DR   KEGG; sasa:106613924; -.
DR   OMA; GWMDCAG; -.
DR   OrthoDB; 4386at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa10.
DR   Bgee; ENSSSAG00000071052; Expressed in brain and 2 other cell types or tissues.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042043; F:neurexin family protein binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007416; P:synapse assembly; IEA:UniProt.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   InterPro; IPR000460; Nlgn.
DR   PANTHER; PTHR43903; NEUROLIGIN; 1.
DR   PANTHER; PTHR43903:SF2; NEUROLIGIN-1; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   PRINTS; PR01090; NEUROLIGIN.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        722..745
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          57..651
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          188..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          673..706
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          842..866
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   866 AA;  97386 MW;  01D0A24289684AA7 CRC64;
     MPLQRPGHLR LHPTWRAMQP RLGVGLGLGL DLTFLLWILS LAQQALVTAS QKLDETDPVV
     TTVYGKLRGV KKELNNEILG PVIQFQGVPY AAPPTGERRF QPPEPPISWP EVRNATQFGP
     VCPQTIVEGR LPDVMLPVWF TNNLEIVSSY VQDQSEDCLF LNIYVPTEDV KRISKECARK
     PGKKICRQGG PLTKKHNDDL GDNDGAEDED IRESGSPKPV MVFIHGGSYM EGTGNMFDGS
     ILASYGNVIV ITVNYRLGVL GFLSTGDQAS KGNYGLLDLI QALRWTSENI AFFGGDPLRI
     TVFGSGAGAS CVNLLTLSHY SEGNRWSNST KGLFQRAIAQ SGTALSSWAV SFQPAKYARM
     LAKKVGCNLK DTVDLVECLQ KKHYKELVDQ DIQPARYHIA FGPVIDGDVI PDDPQILMEQ
     GEFLNYDIML GVNQGEGLKF VELIVDNENG VQANDFDYAV SSFVDDLYGY PEGKDILRET
     IKFMYTDWAD RYNPETRRKT LLALFTDHQW VAPAVATADL HSSFGSPTYF YAFYHHCQTD
     QVPPWADASH GDEIPYVFGL PMIGPTELFP CNFSKNDIML SAVVMTYWTN FAKTGDPNQP
     VPQDTKFIHT KPNRFEEVAW TRYNQKDQLY LHIGLKPRVK EHYRANKVNL WLELVPHLHS
     LNEVTQIIST TTKVPPPEVT PRTPKKIPVN TKRPNPPPFP TETQDSQNQP FLVDQRDYST
     ELSVTIAVGA SLLFLNILAF AALYYKKDKR RHDVHRRCSP QRNTTNDLAH TQEEEIMSLQ
     MKHTDLDHEC DAMHPHKVVL RTACPPDYTL AMRRSPDDIP LMTPNTITMI PNTMQGRQSL
     HNFNTFPSSG QNNTLPHPHS HSTTRV
//