ID A0A1S3TSN2_VIGRR Unreviewed; 530 AA.
AC A0A1S3TSN2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Protein DETOXIFICATION {ECO:0000256|RuleBase:RU004914};
DE AltName: Full=Multidrug and toxic compound extrusion protein {ECO:0000256|RuleBase:RU004914};
GN Name=LOC106758362 {ECO:0000313|RefSeq:XP_014496779.1};
OS Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_014496779.1};
RN [1] {ECO:0000313|RefSeq:XP_014496779.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_014496779.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199,
CC ECO:0000256|RuleBase:RU004914}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU004914}.
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DR RefSeq; XP_014496779.1; XM_014641293.2.
DR GeneID; 106758362; -.
DR KEGG; vra:106758362; -.
DR OrthoDB; 10858at2759; -.
DR Proteomes; UP000087766; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR11206:SF124; PROTEIN DETOXIFICATION 53; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU004914};
KW Reference proteome {ECO:0000313|Proteomes:UP000087766};
KW Transmembrane {ECO:0000256|RuleBase:RU004914};
KW Transmembrane helix {ECO:0000256|RuleBase:RU004914}.
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 217..239
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 291..312
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 373..394
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 448..466
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT TRANSMEM 472..493
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004914"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 58144 MW; 1D02397F1958B8FB CRC64;
MCTGAETGGT VEGNPVSKSK VGHEKQXRSR EGTRNCGCGR FFHDLPQQLH NLLKELFPTL
SLSEVKEEFK SLANIACPIM VTNVLLYSRS AISMLFLGRQ GKVELAGGAL AIGFANITAN
SFLKGLTMGM DPICCQAYGA KRWSVLSQTF FKTLCLLFLV AIPISLLWLN MAPLLHWLGQ
DPEVTQVAQV YMLFSIPELL AQVHLNPLRS FLRTQGLTAP LTVAASFAAI LHLPINYFFA
TYLKLGVKGI ALATGLNSIN MILGLVLYLL VSEKPLKPWE GATILSSFRD WRPLLTLALP
SCVSVCLEWW CYEIMLFLCG MLSNPQTTVA TMGVLIQTTG FLYVFPFSLS AALTTQIGHS
LGAGQPLRAQ STATIGLFIA FASGVSAFVF LMFVRKVWGK LFTTETQIVD MVKTILPILG
LCEIGNWPQT AACGILSGTA RPYVGARINL FAFYLIGLPV AAAFMHRYQL RGLWFGMLAA
QISCFCMMVY TLIQTDWGHQ SKRAEQLART TDDEENVNDD GECGLLNSDL
//
