ID A0A1S3U4P3_VIGRR Unreviewed; 1983 AA.
AC A0A1S3U4P3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Histone-lysine N-methyltransferase ASHH2 isoform X1 {ECO:0000313|RefSeq:XP_014500970.1, ECO:0000313|RefSeq:XP_014500971.1};
GN Name=LOC106761887 {ECO:0000313|RefSeq:XP_014500970.1,
GN ECO:0000313|RefSeq:XP_014500971.1};
OS Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_014500971.1};
RN [1] {ECO:0000313|RefSeq:XP_014500970.1, ECO:0000313|RefSeq:XP_014500971.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_014500970.1,
RC ECO:0000313|RefSeq:XP_014500971.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014500970.1; XM_014645484.2.
DR RefSeq; XP_014500971.1; XM_014645485.2.
DR STRING; 3916.A0A1S3U4P3; -.
DR GeneID; 106761887; -.
DR KEGG; vra:106761887; -.
DR OrthoDB; 54704at2759; -.
DR Proteomes; UP000087766; Chromosome 5.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046975; F:histone H3K36 methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd19172; SET_SETD2; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR006560; AWS_dom.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR044437; SETD2/Set2_SET.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR22884:SF413; HISTONE-LYSINE N-METHYLTRANSFERASE CG1716-RELATED; 1.
DR PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR Pfam; PF17907; AWS; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00570; AWS; 1.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS51215; AWS; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087766};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 946..1000
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 1060..1110
FT /note="AWS"
FT /evidence="ECO:0000259|PROSITE:PS51215"
FT DOMAIN 1112..1229
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1237..1253
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 134..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1267..1350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1708..1746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..162
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..454
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 854..880
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1375..1389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1390..1418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1724..1743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1983 AA; 218103 MW; 011733FF1F75A72C CRC64;
MRSCGRSATV NDPSGGSVIE QHLYSEVAEQ VVSVQESCLE VACNVVDSNA DLSTVTDGYE
GEDFVGSARC IDEGSCDALG LASECENADL LSLEKPAEDD CLNCLGVSYG GIEVPCASSG
PEGNFQGEEN FDLRSRPLTT DDSPRHCAQQ DGQKDDKSHV SPAAGDESVV GGKIDDTCLL
GDVFNHVLDF RDSEMSLELE SVADLLVDCN QQNEQQEMMR NADSLFNVVE KCDNLIGTEA
DACRHISPTV DMEVPSGALY ADTEVDSTSD PKDGEVQNST CEEKVKSFVD EEIIVINSCV
KMSSSPGCQG TVESSSVDSP CEPALLDPGC EMKNDVLQIE DAFCKLKDCS SEETSNSTFR
KPFSPESGLP WVASIANCSS KDVSDLHCKG DDVSTPTATN NAVDDPGKMV NDGKEALNVD
CITESIPLLS QRSSRRSKVG RKTQTKKASR RGKNKTKVTC PNGDYMKLYS EAARKKRSCF
SKPARSSIWG LIGNIEHFFE HDSEHAVREA VCQEFGKARS KRQSGKAVKN NASTGSLSSV
KKCPVSTTRV RLKIKFGKEP DLSCSNVLTP ESVDGLASAS YLESGSASQK IASNLEDKML
KVVTLGNTES FNNNVDKDDL VRNGQVANSP IEGHTEITEK ADGDVEEHCL AAPPEKVIEA
LIEPINNKGM DPGTSPDSEV INSIPEVHVA ERHEEDLHDA VLGSSKELNS KVDATVSKRG
KKKDKLISSG ICITEDESQG PPRNRRGKQS KNRRGKKNCT GAISSLDLST PTQINKSVSS
KQLCPESLSL SGETELGRTA EALKVKNDMD INTSCKPSVD NGFSESQVSE NMLSSARPLG
RKLPKSLRPS KVSRTKFKAS DSADRKKTTC TRKEKQKKPI VKSEVKRKGA SLKITCEMED
RPHAEANIGN HKLDAIRKIN AEDNKVSVNI SSLDTLSGVG LGGQLPSPRN AWVRCDDCYK
WRRIPAVLAD LIDETNRTWT CKDSSDRAFA DCAVPQEKSN AEINAELGLS DASGDEDAYE
GSKNFKELEY RPPFVSQGST FTHIFTNEFL HRSHKTQTID EIMVCHCKAP QEGKFGCGDE
CLNRMLNIEC AQGTCPCGDR CSNQQFQKRK YASLRWFKCG KKGYGLKALG NVAKGQFLIE
YVGEVLDMQT YEARQREYAL KGHRHFYFMT LNGSEVIDAS AKGNLGRFIN HSCDPNCRTE
KWMVNGEICI GLFALRDIKQ DEELTFDYNY VRVFGAAAKK CYCGSPSCRG YIGGGDPLNA
ELIVQSDSEE EFPEPVMLTR DGKIEEAPKY CNNDDTESAR NMLKGRDVLE KSTSAIDSDG
SPEKESSMNP TSAVSLLQSS AEMEDSKGKL PSAIRVEEIS QQMEDVTSKP MPAVQGYEKE
KESEFADKTS PTQRLETTSP LTASSKILTN STGSNRESKS EIIEGKKNPK LNGSVKKGKV
HTSPPNGLKA EVTANRLQLS SVKHKKVEGS SNGRFEAVQE KLNELLDGDG GISKRKDATK
GYLKLLFLTV ASGDRSNGEA IQSNRDLSMI LDALLKTKSR AVLNDIINKN GLQMLHNIMK
QYRQDFKKIP ILRKLLKVLE YLAASKILTP EQINGGPPCH GMESFRESML SLTEHDDKQV
HQIARSFRDR WFPRPNRKHG YLDRDDNRME SHRTFNGNRF SASHCHRHEQ DLRAAEVIDC
SQQSMHVTTP VDADTQESCP AHSVDVVEIK GPKKRKRKSR WDQPGESNSL SDAVMSSVGE
SQNIHEDVPP GFSCPLNASS LNSGNLVLQN ASRSGCPSDL VVGHSKRKFN SRLPVAYGMP
WSVAQQYGTP HTEFPERWVT APGIPFVPFP PLPPYPRDNK DSQPSNNYIA MIIDQPAEAM
TRDHSAEVKE GDNSSMVTCC ADDMIPSTTS ANPEESNLLF EDNEAKRMKG DSHDLVTKYY
RQQKWNNSKI HRPWFRRNAW KCNENNSNGD MCSIGVDVPK ESEDTCDAED AICREEKGGN
NIY
//
