ID   A0A1S3U5J7_VIGRR        Unreviewed;       936 AA.
AC   A0A1S3U5J7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Exosome complex exonuclease RRP44 homolog A isoform X2 {ECO:0000313|RefSeq:XP_014501295.1};
GN   Name=LOC106762099 {ECO:0000313|RefSeq:XP_014501295.1};
OS   Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX   NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_014501295.1};
RN   [1] {ECO:0000313|RefSeq:XP_014501295.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_014501295.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC       {ECO:0000256|ARBA:ARBA00005785, ECO:0000256|RuleBase:RU003901}.
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DR   RefSeq; XP_014501295.1; XM_014645809.2.
DR   AlphaFoldDB; A0A1S3U5J7; -.
DR   GeneID; 106762099; -.
DR   OrthoDB; 945235at2759; -.
DR   Proteomes; UP000087766; Chromosome 5.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   CDD; cd09862; PIN_Rrp44-like; 1.
DR   Gene3D; 2.40.50.690; -; 1.
DR   Gene3D; 2.40.50.700; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   InterPro; IPR033771; Rrp44_CSD1.
DR   InterPro; IPR033770; RRP44_S1.
DR   PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF13638; PIN_4; 1.
DR   Pfam; PF00773; RNB; 1.
DR   Pfam; PF17216; Rrp44_CSD1; 1.
DR   Pfam; PF17215; Rrp44_S1; 1.
DR   SMART; SM00670; PINc; 1.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE   3: Inferred from homology;
KW   Exonuclease {ECO:0000313|RefSeq:XP_014501295.1};
KW   Exosome {ECO:0000256|ARBA:ARBA00022835};
KW   Hydrolase {ECO:0000313|RefSeq:XP_014501295.1};
KW   Nuclease {ECO:0000313|RefSeq:XP_014501295.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087766};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          53..166
FT                   /note="PIN"
FT                   /evidence="ECO:0000259|SMART:SM00670"
FT   DOMAIN          473..804
FT                   /note="Ribonuclease II/R"
FT                   /evidence="ECO:0000259|SMART:SM00955"
SQ   SEQUENCE   936 AA;  105475 MW;  A9E34FE8928CF9A6 CRC64;
     MLHNKSFVKK TRAGKVMKQV REHYLRDDIY CGAPFCTVCD TSGARLNASP STIILVVDTN
     VVLHQIDLLE NQAFDNIVVL SIVLEEVKNK NMAVYNRIRA LCSNATKKFY VFSNEYHRDT
     YVKEMSGETK NDRNDRAIRV ATQWYQNHLG GAVKVLLITN DRENKRKASE EGIFAETVES
     YVKSLDQPDL LDLLVRPASE DVNMEDVEDL RPSKRKVIYS EHKPMSEITS GLHRGIYYQG
     KLRVNRYNPF EAYVGRESIG DEIVIYGRSN MNRAFDGDIV AAELLPQDQW QEVSSLSIAG
     EEDENEDEDV HLAPNSADVA PRTTTQQGSS GQVNAVPTNR PSGRIVGIIK RNWHSYCGSL
     EPMPLPAGSG GIAHALFVSK DRRIPKIRIQ TRQLDNLLDK RIIVAVDSWD RQSRYPSGHY
     VRTIGEIGDR DTESEVVLIE NDINTRPFSS QVLACLPPLP WLVSSEDLSN PIRQDLRHLL
     VFSVDPPGCK DIDDALHCHA LPNGNFEVGV HIADVTNFVH PGTPLDDEAS QRGTSVYLVE
     RRIDMLPKPL TEDICSLRSD VERLAFSVIW EMTPEADVIS TRYTKSVIKS SAALSYVEAQ
     ARMDDSRLRD PITTGLRNMN SLAKKMRLRR IERGALTLAS AEVKFQIDTE THDPLDIGMY
     QIREANQMVE EFMLAANVSV AQQILKSFSL CSLLRRHPTP TREMLEPLLQ TAAAVGLHLD
     VSSSKALADS LDHAVGDDPY FNKLIRILAT RCMSQAVYFC SGDLSPPEYH HYGLAAPLYT
     HFTSPIRRYA DVIVHRLLAA SLGISKLPSV FQDRLQLSSI ADNLNYRHRN AQHAGRASVE
     LHTLIYFRNR PTDTEARIVK IRSNGFFVFV PKYGIEGPIY LTKAGKGNGE WYVDEQQQKI
     KRMDGSLSYS VLQTVQIHME VVEPQPNRPK LQLTLI
//