ID   A0A1S3U9K2_VIGRR        Unreviewed;       954 AA.
AC   A0A1S3U9K2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=DNA topoisomerase 2-binding protein 1-A isoform X4 {ECO:0000313|RefSeq:XP_014502700.1};
GN   Name=LOC106763050 {ECO:0000313|RefSeq:XP_014502700.1};
OS   Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX   NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_014502700.1};
RN   [1] {ECO:0000313|RefSeq:XP_014502700.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_014502700.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_014502700.1; XM_014647214.2.
DR   AlphaFoldDB; A0A1S3U9K2; -.
DR   GeneID; 106763050; -.
DR   OrthoDB; 449768at2759; -.
DR   Proteomes; UP000087766; Chromosome 6.
DR   GO; GO:0005694; C:chromosome; IEA:UniProt.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   CDD; cd00027; BRCT; 1.
DR   CDD; cd17731; BRCT_TopBP1_rpt2_like; 2.
DR   Gene3D; 3.40.50.10190; BRCT domain; 6.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR   PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR   Pfam; PF00533; BRCT; 2.
DR   Pfam; PF12738; PTCB-BRCT; 2.
DR   SMART; SM00292; BRCT; 6.
DR   SUPFAM; SSF52113; BRCT domain; 5.
DR   PROSITE; PS50172; BRCT; 5.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000087766}.
FT   DOMAIN          105..189
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          187..276
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          346..438
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          535..623
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          636..719
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          460..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          901..954
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..477
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        921..936
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   954 AA;  106634 MW;  49FE33923CA36A5B CRC64;
     MLKTKTLKMK AFQGANVFMS RNLVPPEVFD ALHDAVKDNG AQLHLCCDPS RNGPDDYHII
     ASSKHEKFDD LKSKGCKLLG PRCVLSCAKG GRPLPKQGFT CCLAMDGVKV LASGFDTEEK
     VKIEELVAEM GGVLHTKTSL DLNFVIVKNV LARKYKWALN ELKKPIVTYE WLKQCSEEHR
     VVPQESYKVL PFSGLKICVT GIPADVRKEM EKLILQNGGK YSAELTKNCT HLISEAPQGD
     KYKVAKRWGH IHIVIKKWFD QSIARRACLN EEFFPVQHGS VSSHKVTRDL TMQHSQEKDI
     GKLQSAASSD SQTRIFAKEA DAEPPLQTSG ELNLDNIVAD DSESDDNDLY LSECRILLVG
     FEALEMRKLI NIVRKGGGSR YMSFNDKLTH IVVGNPTEME KKDVRSLAAL GVIYVVKTSW
     LEDCDHKKKE VPVLRRHIAY DLLQPKASLV KAVTESTSMD HSKSSSCHQS SHQVDFENVK
     PESLEKRKEQ IKDMDINGHS FRKANCRTML QNQLPDNKLS TQGMSQHDFS VQYEKSANVF
     RGKLFCFSNL FPEEKRGEIV QWISQGGGEV ISGQAEQIVH YTVECHGVTP MLTGDSKSLS
     VSSHWIRSCL EAGSLLDVGS HILYSPLPCH VPLPGFERFR FCVSQYEEKD RNLLRNLCFV
     LGAKFGEKLH KKVTHLLCKF TNGPKYDGAR KWGIQSVTCE WIFECVKQNG VVAVDQFLPK
     EVTAQDREAG LCTVSQFPTQ AAQMISDMPS QLSSQSQILR GITDKNVGCG VGNHETNFKK
     PSVYSKKARL VEEPCLSNKM PSASNSGIHA YGKNFSEDNT LIDGGEVCRT VPDVAAAIED
     LLEQTSKMHG QRSPAHTGCE RGIYPSDLSV LGEDNSNPHT VFGLSKHWLN STESIYSYRN
     DRKEDDGEAS QDRPAGIYDG FSETQTESQV VSYEEDLSGR QSLIDKYRTR SSTQ
//