ID A0A1S3V8T7_VIGRR Unreviewed; 858 AA.
AC A0A1S3V8T7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU364117};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU364117};
GN Name=LOC106772714 {ECO:0000313|RefSeq:XP_014514758.1};
OS Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_014514758.1};
RN [1] {ECO:0000313|RefSeq:XP_014514758.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_014514758.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU364117};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364117}.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446, ECO:0000256|RuleBase:RU364117}.
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DR RefSeq; XP_014514758.1; XM_014659272.2.
DR AlphaFoldDB; A0A1S3V8T7; -.
DR GeneID; 106772714; -.
DR OrthoDB; 1207998at2759; -.
DR Proteomes; UP000087766; Chromosome 8.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF69; ATP-DEPENDENT DNA HELICASE Q-LIKE SIM; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU364117};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU364117};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU364117};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU364117};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364117};
KW Reference proteome {ECO:0000313|Proteomes:UP000087766}.
FT DOMAIN 5..51
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 156..332
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 487..645
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 386..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..843
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 97912 MW; 307474BC106622DE CRC64;
MGRNAMDGND TCWDKVIAEM IEMGFEHSSI VEAIKVVGPS VPSAVEHILN STTEEPSTTH
TSNSHARNGN ALKKRPLRKC LVRQSNIFDH FRSNDDVEEH KKEIPQLGIK PNPIVLSEPF
EAQDLDVESD WEQKTSNLMK KHFGFSSLKS FQKEAISAWV VHKDCLVLAA TGSGKSLCFQ
IPALFSGKVV VVISPLISLM HDQCLKLTRH GISACFLGSG QPDNTVEQKA MRGLYSIVYI
CPETVLRLIQ PLQKLAESRG IALFAIDEVH CVSKWGHDFR PDYRRLSVLR ENFSTSKLKS
LKFDIPLMAL TATATKRVRE DILKSLQMSK ETKVCLTSFF RPNLRFMVKH SRVSQASYAK
DFHELIRVYG RKKNIDEKEK VFISDDSDQI SNSSDASSIS DTDSVSPDDM DDNQDDYAYR
DINIMHSGNS DDFLTGKELS IEFLENDIDA FQSMDNLDVA RGDFCVLPHK ELELSKNTNI
PKKPEGRVKI LNEPLEQGPT IIYVPTRKET LRIAKYLCKF GLKAAAYNAG LPKLHLRKVH
KEFHENGLEV IVATIAFGMG IDKSNVRRII HYGWPQSLEA YYQEAGRAGR DGKLSDCILY
ANLASKPSLL PSRKSEDQKK QAYIMLSDCF RYGMNTSCCR AKILVEYFGE DFGHQKCHLC
DVCIDGPPKK QNLKEEACIF LQTIGAQNGR RDSKDYSYDD DIHFDYNYRG QRERPNLRML
VGKIRQQFQK FSTTDMLWWR GLARILEVKG YIREGDDKSH VQAKFPEFVR SMNEEAFWVY
PEADMLLARK LTEKPFSSFS EWGKGWADPE IRRQRLERMG VKRKSGMVSS SKRKPKRKVQ
HDLRTSRGRL TAKLSKYK
//
