ID A0A1S3V9B1_VIGRR Unreviewed; 495 AA.
AC A0A1S3V9B1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=fumarate hydratase {ECO:0000256|ARBA:ARBA00012921};
DE EC=4.2.1.2 {ECO:0000256|ARBA:ARBA00012921};
GN Name=LOC106772793 {ECO:0000313|RefSeq:XP_014514870.1};
OS Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX NCBI_TaxID=3916 {ECO:0000313|Proteomes:UP000087766, ECO:0000313|RefSeq:XP_014514870.1};
RN [1] {ECO:0000313|RefSeq:XP_014514870.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_014514870.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class-II fumarase/aspartase family. Fumarase
CC subfamily. {ECO:0000256|ARBA:ARBA00009084}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014514870.1; XM_014659384.2.
DR AlphaFoldDB; A0A1S3V9B1; -.
DR STRING; 3916.A0A1S3V9B1; -.
DR GeneID; 106772793; -.
DR KEGG; vra:106772793; -.
DR OrthoDB; 1341425at2759; -.
DR Proteomes; UP000087766; Chromosome 8.
DR GO; GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
DR GO; GO:0004333; F:fumarate hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006106; P:fumarate metabolic process; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR CDD; cd01362; Fumarase_classII; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR HAMAP; MF_00743; FumaraseC; 1.
DR InterPro; IPR005677; Fum_hydII.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR018951; Fumarase_C_C.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR NCBIfam; TIGR00979; fumC_II; 1.
DR PANTHER; PTHR11444; ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE; 1.
DR PANTHER; PTHR11444:SF1; FUMARATE HYDRATASE, MITOCHONDRIAL; 1.
DR Pfam; PF10415; FumaraseC_C; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000087766}.
FT DOMAIN 43..373
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 439..491
FT /note="Fumarase C C-terminal"
FT /evidence="ECO:0000259|Pfam:PF10415"
SQ SEQUENCE 495 AA; 53259 MW; 4CBF018631D4DB0C CRC64;
MALYAVSRRL SAGSNSTTLL ALRFASSSRS YSSSFREERD TFGPIQVPSD KLWGAQTQRS
LQNFDIGGPR ERMPEPIIRA FGVLKKCAAK VNMDYGLDPN VGKAIMQAAQ EVAEGKLNEH
FPLVVWQTGS GTQSNMNANE VIANRAAEIL GHKRGDKFVH PNDHVNRSQS SNDTFPTVMH
IAAAMEINSR LIPSLKTLHG TLNSKSIEFK DIVKIGRTHT QDATPLTLGQ EFSGYTTQVK
YGIDRVIGTL PRMYQLAQGG TAVGTGLNTK KGFDAKIAAA VADETNLPFV TAENKFEALA
AHDAFVETSG ALNTIAASLM KIANDIRLLG SGPRCGLGEL ILPENEPGSS IMPGKVNPTQ
CEALTMVCAQ VMGNHVAVTV GGSNGHFELN VFKPMIASCL LHSLRLLGDS SASFEKNCVR
GIQANRERIS KLLHESLMLV TSLNPKIGYD KAAAVAKTAH KEGTTLKEAA LKLGVLSSEE
FDKLVVPEKM LGPSD
//
