ID A0A1S3W9U2_ERIEU Unreviewed; 472 AA.
AC A0A1S3W9U2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Cytokine-like nuclear factor N-PAC {ECO:0000256|ARBA:ARBA00034140};
DE AltName: Full=Glyoxylate reductase 1 homolog {ECO:0000256|ARBA:ARBA00030287};
DE AltName: Full=Nuclear protein NP60 {ECO:0000256|ARBA:ARBA00032038};
DE AltName: Full=Putative oxidoreductase GLYR1 {ECO:0000256|ARBA:ARBA00034145};
GN Name=GLYR1 {ECO:0000313|RefSeq:XP_016043141.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016043141.1};
RN [1] {ECO:0000313|RefSeq:XP_016043141.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
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DR RefSeq; XP_016043141.1; XM_016187655.1.
DR AlphaFoldDB; A0A1S3W9U2; -.
DR CTD; 84656; -.
DR OrthoDB; 103196at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05836; PWWP_GLYR1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR035501; GLYR1_PWWP.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 8..66
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
SQ SEQUENCE 472 AA; 51585 MW; FA9C16D4B0BF20E5 CRC64;
MAAVSLRLGD LVWGKLGRYP PWPGKIVNPP KDLKKPRGKK CFFVKFFGTE DHAWIKVEQL
KPYHAHKEEM IKINKGKRFQ QAVDAVEEFL RRAKGKDQDL TIPESSTVKG MMAGPMAAFK
WQPTVNEPVK DADPHFHHFL LSQTEKPTVC YQAITKKLKI CEEETGSTSI QAADSTAVNG
SITPTDKKIG FLGLGLMGSG IVSNLLKMGH TVTVWNRTAE KCDLFIQEGA RLGRTPAEVV
STCDITFACV SDPKAAKDLV LGPSGVLQGI RPGKCYVDMS TVDADTVTEL AQVIVSRGGR
FLEAPVSGNQ QLSNDGMLVI LAAGDRGLYE DCSSCFQAMG KTSFFLGEVG NAAKMMLIVN
MVQGSFMATI AEGLTLAQVT GQSQQTLLDI LNQGQLASIF LDQKCQNILQ GNFKPDFYLK
YIQKDLRLAI ALGDAVNHPT PMAAAANEVY KRAKALDQSD NDMSAVYRAY IH
//
