ID   A0A1S3WDK0_ERIEU        Unreviewed;      1244 AA.
AC   A0A1S3WDK0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Protein strawberry notch homolog 2 isoform X2 {ECO:0000313|RefSeq:XP_016044461.1};
GN   Name=SBNO2 {ECO:0000313|RefSeq:XP_016044461.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016044461.1};
RN   [1] {ECO:0000313|RefSeq:XP_016044461.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SBNO family.
CC       {ECO:0000256|ARBA:ARBA00006992}.
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DR   RefSeq; XP_016044461.1; XM_016188975.1.
DR   AlphaFoldDB; A0A1S3WDK0; -.
DR   CTD; 22904; -.
DR   OrthoDB; 3541637at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR026937; SBNO_Helicase_C_dom.
DR   InterPro; IPR026741; SNO.
DR   InterPro; IPR039187; SNO_AAA.
DR   PANTHER; PTHR12706:SF5; PROTEIN STRAWBERRY NOTCH HOMOLOG 2; 1.
DR   PANTHER; PTHR12706; STRAWBERRY NOTCH-RELATED; 1.
DR   Pfam; PF13872; AAA_34; 1.
DR   Pfam; PF13871; Helicase_C_4; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT   DOMAIN          139..429
FT                   /note="Strawberry notch AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13872"
FT   DOMAIN          653..931
FT                   /note="Strawberry notch helicase C"
FT                   /evidence="ECO:0000259|Pfam:PF13871"
FT   REGION          102..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..602
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1213..1244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..121
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..560
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        576..593
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1244 AA;  137381 MW;  AA1E24D24C2CD898 CRC64;
     MRGPAGPPAM SRLHLWLRLA GLHQDAAYLE DLSTSSLDSL SDIADTPDFP AADSLSQVPT
     IWDVVSPGPA PDKLFLPGGP FPGLEDPAPG LPSTPLLVSY QSQSHVEEEE EPEEEEAEEL
     GHTETYADYV PSKSKIGKQH PDRVVETSTL SSVPPPDVTY SLAVPTADSG ALSALQLEAI
     TYACQQHELL LPGGQRAGFL IGDGAGVGKG RTVAGIILEN HVRGRKKALW FSVSNDLKYD
     AERDLRDIHA PGIAVHVLSK IKYGDNTTSE GVLFATYSAL IGESQAGGQH RTRLRQILEW
     CGSAFDGVIV FDECHKAKNA SSTKMGKAVL DLQSQLPLAR VVYASATGAS EPRNMVYMSR
     LGIWGEGTPF RTFEDFLHAI DKRGVGAMEI VAMDMKVSGM YIARQLSFSG VTFRIEEIPL
     APAFERVYNS AALLWAEALA VFQQAADWLG LESRKSLWGQ FWSAHQRFFK YLCVAAKVRR
     LVELARQELA RDKCVVIGLQ STGEARTREV LDQKEGQLNC FVSAAEGVFL SLIQKHFPSC
     KRKRERAGCK RKRRPRGRTP KAPRTMAELP PVIHISDDSS SESDAALDSD SHSSPESLAD
     DDVVLVEPLR LPAEERGPPP REPQGPGVLE RVEQLKQELL AKVRALGREL PANTLDQLIH
     QLGGPGHVAE MTGRKGRVVS RPDGTVAFES RAEQGLSIDH VNLREKERFM SGEKLVAIIS
     EASSSGVSLQ ADRRVLNQRR RVHMTLELPW SADRAIQQFG RTHRSNQVSA PEYVFLISEL
     AGERRFASIV AKRLESLGAL THGDRRATES RDLSKYNFEN KYGKRALSCV LATVQSHADS
     PVPLPRGYPG GDAAFFRDMK QGLLSVGIGG RESRSGGLDM EKDCSITKFL NRILGLEVHK
     QNALFQYFSD TFDHLIDRDK KEGKYDLGIL DLAPGVDEIY EESQQVFQTP GHPQDGQVVL
     YKVTVDRGLR WEQAFAKSLE LTGPHDGFYL SYKARGNQPS CLLAEQNRGK LFTVYKPNIG
     RQSQLETHDS LGRRFHQVPA EEAREHWENS FNFSLTQCSH VAWNRQCRLA QEGRECSQGL
     RLRHHYVLCG ALLRVWGRVA AVMAEVTGSN HLQIVRLKTK DQKKQVGIKV PEVCVRRVLR
     ELQLMDADVK RKNARPPPPC PPALGPHPEV LDLTHSPPAA RPPPFAFPPA LLEPDINYKE
     VLEEMLRFQA EPRASGAERG SVIQFGPPFP EAAATGRAGG PADY
//