ID   A0A1S3WDZ8_ERIEU        Unreviewed;       336 AA.
AC   A0A1S3WDZ8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Fatty acid desaturase 6 {ECO:0000313|RefSeq:XP_016044560.1};
GN   Name=FADS6 {ECO:0000313|RefSeq:XP_016044560.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016044560.1};
RN   [1] {ECO:0000313|RefSeq:XP_016044560.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_016044560.1; XM_016189074.1.
DR   AlphaFoldDB; A0A1S3WDZ8; -.
DR   GeneID; 103115428; -.
DR   CTD; 283985; -.
DR   eggNOG; ENOG502QQ1J; Eukaryota.
DR   InParanoid; A0A1S3WDZ8; -.
DR   OrthoDB; 4345982at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   PANTHER; PTHR19353:SF13; FATTY ACID DESATURASE 6; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
PE   4: Predicted;
KW   Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW   Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          59..305
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   336 AA;  37871 MW;  A2CE12A8EE57B2B7 CRC64;
     MELPGRRGEA LLGELETRVR AVVRASSWWE RHGVDCAILA LSLLALPAGF LCLRSGNVLV
     FALGIIILGV CHYTLTVKGS HLATHGALTE SKRWSKIWAL FFVEVCTAFT AEYANYGHVK
     MHHAYTNVLG LGDSSTWRLP YLNRYVYMFL APFLIPIVTP LVAVERLRKM EPAVALRSLG
     LISLGLCSHY WLLMNVSGCT SPGSALACMF ITRSLLAHPY LHVNIFQHIG LPMFSLDTKP
     QRIHMMSLGV LNLPRLPVLD WAFGHSIISC HVEHHLFPRL SDNMCLKVKP VVSQFLQEKQ
     LPYNEDSYLA RFRLFLSRYE EFMVQAPPIT ELVGLQ
//