ID   A0A1S3WH77_ERIEU        Unreviewed;       452 AA.
AC   A0A1S3WH77;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Amyloid beta A4 precursor protein-binding family B member 1 isoform X8 {ECO:0000313|RefSeq:XP_016045746.1};
GN   Name=APBB1 {ECO:0000313|RefSeq:XP_016045746.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016045746.1};
RN   [1] {ECO:0000313|RefSeq:XP_016045746.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_016045746.1; XM_016190260.1.
DR   AlphaFoldDB; A0A1S3WH77; -.
DR   CTD; 322; -.
DR   OrthoDB; 5404780at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR   CDD; cd01272; PTB1_Fe65; 1.
DR   CDD; cd01271; PTB2_Fe65; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039576; APBB1/2/3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR   PANTHER; PTHR14058:SF5; AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1; 1.
DR   Pfam; PF00640; PID; 2.
DR   SMART; SM00462; PTB; 2.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS01179; PID; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT   DOMAIN          112..251
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          284..441
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          1..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..47
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..73
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   452 AA;  49905 MW;  DC4F2A295F6FEBF7 CRC64;
     MRVQDTSGTY YWHIPTGTTQ WEPPGQASSS QGSSPREDSS QLTWTGFTHG EGFEDGEFWK
     DEPNEEAPMD LGIKDPEEGT LPFPAQSLSP EPLPQEEEKL PARNTNPGTK CFAVRSLGWV
     EMTEEELAPG RSSVAVNNCI RQLSYHKNNL HDPMAGGWGE GKDLLLQLED ETLKLVEPQT
     QALLHAQPIV SIRVWGVGRD SGRERDFAYV ARDKLTQMLK CHVFRCEAPA KNIATSLHEI
     CSKIMAERRN ARCLVNGLSL DHSKLVDVPF QVEFPAPKNE LVQKFQVYYL GNVPVAKPVG
     VDVINGALES VLSSSSREQW TPSHVSVAPA TLTILHQQTE AVLGECRVRF LSFLAVGRDV
     HTFAFIMAAG PASFCCHMFW CEPNAASLSE AVQAACMLRY QKCLDARSQA STSCLPAPPA
     ESVARRVGWT VRRGVQSLWG SLKPKRLGAH TP
//