ID   A0A1S3WH92_ERIEU        Unreviewed;       458 AA.
AC   A0A1S3WH92;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=H-2 class I histocompatibility antigen, Q10 alpha chain-like {ECO:0000313|RefSeq:XP_016045499.1};
GN   Name=LOC103117186 {ECO:0000313|RefSeq:XP_016045499.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016045499.1};
RN   [1] {ECO:0000313|RefSeq:XP_016045499.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
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DR   RefSeq; XP_016045499.1; XM_016190013.1.
DR   AlphaFoldDB; A0A1S3WH92; -.
DR   GeneID; 103117186; -.
DR   eggNOG; ENOG502RQEK; Eukaryota.
DR   InParanoid; A0A1S3WH92; -.
DR   OrthoDB; 3840485at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07698; IgC1_MHC_I_alpha3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   PANTHER; PTHR16675:SF134; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..458
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012616556"
FT   TRANSMEM        417..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          324..409
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   458 AA;  52047 MW;  354479E01289C70C CRC64;
     MSGGAWLLTV RGLAGVTWRS CATSAGVRFA GPRRYPKFGL QLHRPQAAGD RRRQTPRQLF
     LWSSARLAAW DPRDPRDPRD LPGPRSACTW LLLLSLLLSL GPRAAAESPW GLPPVEDGSA
     SSAKKLMAEL ASLKLENTSW PGGRHTLHYH YLFLSESGPN LPLFLAVGYM NDQPFIRFDS
     RVGKAEPCAL WMAAVESWYW DTETEKQRGW KEVQKVEMKR VMAYHNHSSG THTTQRMFGC
     EIKKDGKISG FWQFGYDGQD HLTLDLENLS WVSANSVALQ KKRFLERQRC YAEYNKAYLS
     SLCLLSLRRY LELGGLNLTR REPPTVQVTR HLAQDGGAIL RCWARGFYPR DISVSWWVGE
     EELSQETEWV ETRPSGDGTY QTWMAVRVLE KKSSYTCRVQ HSGLNYTLTE TWESPSLGGL
     SALVIPFGLI VVAIVMFWRW FQARKKETSQ QSPGREPA
//