ID   A0A1S3WJQ0_ERIEU        Unreviewed;       455 AA.
AC   A0A1S3WJQ0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=NAD(+) kinase {ECO:0000256|ARBA:ARBA00012120};
DE            EC=2.7.1.23 {ECO:0000256|ARBA:ARBA00012120};
GN   Name=NADK {ECO:0000313|RefSeq:XP_016046512.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016046512.1};
RN   [1] {ECO:0000313|RefSeq:XP_016046512.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NAD kinase family.
CC       {ECO:0000256|ARBA:ARBA00010995}.
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DR   RefSeq; XP_016046512.1; XM_016191026.1.
DR   AlphaFoldDB; A0A1S3WJQ0; -.
DR   GeneID; 103119252; -.
DR   CTD; 65220; -.
DR   eggNOG; KOG2178; Eukaryota.
DR   InParanoid; A0A1S3WJQ0; -.
DR   OrthoDB; 455155at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR   GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   HAMAP; MF_00361; NAD_kinase; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR002504; NADK.
DR   PANTHER; PTHR20275; NAD KINASE; 1.
DR   PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR   Pfam; PF01513; NAD_kinase; 1.
DR   Pfam; PF20143; NAD_kinase_C; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_016046512.1};
KW   NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   REGION          436..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..455
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   455 AA;  50106 MW;  40FAE7715B33A02D CRC64;
     MVDMEQERVS MSKELGSASA TYRCSACHGD EDWGLGHPIR GRAKSRSLSA SPALASTKEF
     RRTRSLHGPC PVTTFGPKAC VLQNPQTIMH IQDPASQRLT WNKSPKSVLV IKKIRDASLL
     QPFKELCMYL MEESNMIVYV EKKVLEDPAI VSDDNFGPVK KKFCTFREDY DDISNQIDFI
     ICLGGDGTLL YASSLFQGSV PPVMAFHLGS LGFLTPFNFE NFQSQVTQVI QGNAAVVLRS
     RLKVKVVKEL RGKKTAIPNG LSENGVLAAG LDIEAGKQVM QYQVLNEVVI DRGPSSYLSN
     VDVFLDGHLI TTVQGDGVIV STPTGSTAYA AAAGASMIHP NVPAIMITPI CPHSLSFRPI
     VVPAGVELKI MLSPEARNTV WVSFDGRKRQ EIRHGDSISI TTSCYPLPSI CVQDPVSDWF
     ESLAQCLHWN VRKKQTHFTE EEEEEEEEKE GGEEG
//