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Database: UniProt
Entry: A0A1S3WLL0_ERIEU
LinkDB: A0A1S3WLL0_ERIEU
Original site: A0A1S3WLL0_ERIEU 
ID   A0A1S3WLL0_ERIEU        Unreviewed;       586 AA.
AC   A0A1S3WLL0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 12.
DE   SubName: Full=growth factor receptor-bound protein 7 isoform X4 {ECO:0000313|RefSeq:XP_016047166.1, ECO:0000313|RefSeq:XP_016047167.1};
GN   Name=GRB7 {ECO:0000313|RefSeq:XP_016047166.1,
GN   ECO:0000313|RefSeq:XP_016047167.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae;
OC   Erinaceinae; Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016047167.1};
RN   [1] {ECO:0000313|RefSeq:XP_016047166.1, ECO:0000313|RefSeq:XP_016047167.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   RefSeq; XP_016047166.1; XM_016191680.1.
DR   RefSeq; XP_016047167.1; XM_016191681.1.
DR   GeneID; 103120584; -.
DR   CTD; 2886; -.
DR   OrthoDB; 497681at2759; -.
DR   Proteomes; UP000079721; Genome assembly.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01259; PH_APBB1IP; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR015042; BPS-dom.
DR   InterPro; IPR039664; GRB/APBB1IP.
DR   InterPro; IPR035032; Grb7.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039665; PH_APBB1IP.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11243; PTHR11243; 3.
DR   PANTHER; PTHR11243:SF25; PTHR11243:SF25; 3.
DR   Pfam; PF08947; BPS; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000079721};
KW   Receptor {ECO:0000313|RefSeq:XP_016047166.1,
KW   ECO:0000313|RefSeq:XP_016047167.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      126    212       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      255    364       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      457    581       SH2. {ECO:0000259|PROSITE:PS50001}.
FT   REGION        1     50       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3WLL0}.
FT   COMPBIAS     21     35       Pro-rich. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3WLL0}.
SQ   SEQUENCE   586 AA;  65536 MW;  B6EDA11B8ED10730 CRC64;
     MELGLSPPLL NNSPEELYLS PGTPPRTPPP PDGPLSREVK RSQPLPIPAG RYSALTGQVD
     WWGGSVGSAQ TLPSGHRKLL REEELRATSL PSIPNPFPEL CSPPSQSPIL GGSSGTRGLL
     PRDASRPHVI KVYSEDGACR SVEVAAGATA RYVCEMLVQR AHALSDENWG LVECHPQLAL
     ERGLEDHESV VEVQAAWPIG GDSRFVFRKN FAKYELFKTS PHSLFPEKMV SSCLDAKADT
     SHEDLIQNFL NAGSFPEIQG FLQLRGSGRK LWKRFFCFLR RSGLYYSTKG TSKDPRHLQC
     VADVNESSVY VVTQGRKLYG MPTDFGFCIK PNKLRNGHKG LHIFCSEDEQ SRTCWLAAFR
     LFKYGVQLYK NYQLAQSRHL RPSYVGSPPL RSVSDNTLVA MDFSGHAGRV IENPREALSA
     ALEEAQAWRK KTNHRLSLPT PSSGSSLSAA IHRTQPWFHG RISREESQRL IGQQGLVDGL
     FLVRESQRNP QGFVLSLCHL QKVKHYLILP QWGLQLWSPG EPLQPQLPLT SCPLWSSQSE
     EEGRLYFSMD EGQTRFTDLL QLVEFHQLNR GILPCVLRHT CTRVAL
//
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