ID A0A1S3WMG6_ERIEU Unreviewed; 1411 AA.
AC A0A1S3WMG6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LIM domain only protein 7 isoform X2 {ECO:0000313|RefSeq:XP_016047545.1};
GN Name=LMO7 {ECO:0000313|RefSeq:XP_016047545.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016047545.1};
RN [1] {ECO:0000313|RefSeq:XP_016047545.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016047545.1; XM_016192059.1.
DR CTD; 4008; -.
DR OrthoDB; 6462at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0023051; P:regulation of signaling; IEA:InterPro.
DR CDD; cd08368; LIM; 1.
DR CDD; cd00136; PDZ; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR029978; LMO-7.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR46767; LIM DOMAIN ONLY PROTEIN 7; 1.
DR PANTHER; PTHR46767:SF1; LIM DOMAIN ONLY PROTEIN 7; 1.
DR Pfam; PF15949; DUF4757; 2.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00132; LIM; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 760..841
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1340..1406
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 26..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1240..1334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 945..995
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 489..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1247..1334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1411 AA; 161618 MW; D9040529F18E6DDB CRC64;
MQDYNKDDMS YRRISAIEPK SALPFNRFLP NKSRQPSYVP APLRKKKPDR NEDNRRSWAS
PASSEADGTF SRLDVLSSNE RRTWDTNMEN WSAVQATSHS SRYLEEKEKT NMPNIVKDDL
YVRKLSPVMP NPGNAFNQFL PKCWIPEDVN CKRIKRETYK PWYKEFQGFS QFLLLHALQT
YSDDILSSET NTRIDPTSGP RLITRRKNRF YTPGYRRDDH EISSVNPDLE NDDFFVRKTG
AFHANPCVLQ AFEDFRRFSE QDDPVERDII LQCREGEIVL PDLEKDDMII RRIPAQKKEV
PLSGAPDRYQ PVPFPEPWTL PPEIQAKFLC VLERTCPTRE KSSNSCRVLV PSHRQKKDDM
LTRKIQSWKL GTAVSPISFT PGPCSEADLK KWEAIREASR LRHKKRLMVE RLFQKIYGEN
GSKSMSDVTA EDVQNMRQLR YEEMQKIKSQ LKEQDQKWQD DLAKWKDRRK SYTSDLQKKK
EEREEIEKLA LEKSEKNSKT LKEMQQDRES RNQMTAITSR RRIYSHDDVL NEEIFSPPVT
MSETHDQSER AEEMGTTYPT EIPKHDSTTL VKREDSVAAE IPLPSNSTAE GQRPASLSSQ
LLLSTQMEST RVSTSLPRSY QKTDTARLTS VVTPRPFGSH SRGISSLPRS YTMDAAWKYN
GDVEGVKRTQ NTCVNTSVQK PDPSQLTSSL PSERETVAEE VTRVPSPIAS LSPSSQDQSV
TSQVTLSSTS GLDLMSESGV GRSSPQREVS KSQDQFSDMR ISINQKPGNS IVLGFTVKWD
FSGISIASVE AGSPAEFSQL QVDDEIIAIN NIKFSRKDTK EWEEAMANAQ ETGNLVMDIR
RYGKSGSPET KWIDATSGIY NSDKSSNLSI TTDFSESLQD SNVESKEING IRDERNTFES
KASEPISLKN LKRRSQFFEQ GSSDSMVPDL PVPTISAPSR WAWDQEEERK RQEKWQKEQD
RLLQEKYQRE QEKLREEWQI AMQEAERENS KYLNEELMVL TSNNIALTPR EPEATSWETT
WGVESKSSDK EGTRAGEEER RPQQEDSLTE DQNKKLQEHL SLEKERKLKE EQQYQEEQEQ
KQRQYQEERE LRRRQAEAEA EERARLGEEL KHQAERERET SVKIYQYRRP VDSYDVSGRE
EESSGLLPSD RNKSRSTTEL DDYSSSKNGN NRYLDRIGNT SSLQKSSKKE QAPSGAELER
QQILQEMRKR TSLHNDNSWI RQRSSSVNKE PICLPGIMRR GESLDNLDSP RSNSRRQSPW
HNQSTGVYAS SSVQDFSRPP PQLLSTSNRA YMRNPSSGVP PPSSGSGKTP SAPSPPSRSQ
SPSTTQSGSQ LRNRSVSGKR VCSYCNNILG KGAAMIIESL GLCYHLHCFK CVACERDLGG
SASGAEVRIR NNQLYCNDCY LRFKSGRPTA M
//
