ID A0A1S3WMN2_ERIEU Unreviewed; 1392 AA.
AC A0A1S3WMN2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=LIM domain only protein 7 isoform X4 {ECO:0000313|RefSeq:XP_016047547.1};
GN Name=LMO7 {ECO:0000313|RefSeq:XP_016047547.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016047547.1};
RN [1] {ECO:0000313|RefSeq:XP_016047547.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016047547.1; XM_016192061.1.
DR CTD; 4008; -.
DR OrthoDB; 6462at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0023051; P:regulation of signaling; IEA:InterPro.
DR CDD; cd08368; LIM; 1.
DR CDD; cd00136; PDZ; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR029978; LMO-7.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR46767; LIM DOMAIN ONLY PROTEIN 7; 1.
DR PANTHER; PTHR46767:SF1; LIM DOMAIN ONLY PROTEIN 7; 1.
DR Pfam; PF15949; DUF4757; 2.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00132; LIM; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 760..841
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1321..1387
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 26..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 991..1180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 926..976
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 489..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1114..1141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1392 AA; 159357 MW; 7527160DE90726AF CRC64;
MQDYNKDDMS YRRISAIEPK SALPFNRFLP NKSRQPSYVP APLRKKKPDR NEDNRRSWAS
PASSEADGTF SRLDVLSSNE RRTWDTNMEN WSAVQATSHS SRYLEEKEKT NMPNIVKDDL
YVRKLSPVMP NPGNAFNQFL PKCWIPEDVN CKRIKRETYK PWYKEFQGFS QFLLLHALQT
YSDDILSSET NTRIDPTSGP RLITRRKNRF YTPGYRRDDH EISSVNPDLE NDDFFVRKTG
AFHANPCVLQ AFEDFRRFSE QDDPVERDII LQCREGEIVL PDLEKDDMII RRIPAQKKEV
PLSGAPDRYQ PVPFPEPWTL PPEIQAKFLC VLERTCPTRE KSSNSCRVLV PSHRQKKDDM
LTRKIQSWKL GTAVSPISFT PGPCSEADLK KWEAIREASR LRHKKRLMVE RLFQKIYGEN
GSKSMSDVTA EDVQNMRQLR YEEMQKIKSQ LKEQDQKWQD DLAKWKDRRK SYTSDLQKKK
EEREEIEKLA LEKSEKNSKT LKEMQQDRES RNQMTAITSR RRIYSHDDVL NEEIFSPPVT
MSETHDQSER AEEMGTTYPT EIPKHDSTTL VKREDSVAAE IPLPSNSTAE GQRPASLSSQ
LLLSTQMEST RVSTSLPRSY QKTDTARLTS VVTPRPFGSH SRGISSLPRS YTMDAAWKYN
GDVEGVKRTQ NTCVNTSVQK PDPSQLTSSL PSERETVAEE VTRVPSPIAS LSPSSQDQSV
TSQVTLSSTS GLDLMSESGV GRSSPQREVS KSQDQFSDMR ISINQKPGNS IVLGFTVKWD
FSGISIASVE AGSPAEFSQL QVDDEIIAIN NIKFSRKDTK EWEEAMANAQ ETGNLVMDIR
RYGKSGSPET KWIDATSGIY NSDKSSNLSI TTDFSESLQD SNVESKEING IRDERNTFES
KGSSDSMVPD LPVPTISAPS RWAWDQEEER KRQEKWQKEQ DRLLQEKYQR EQEKLREEWQ
IAMQEAEREN SKYLNEELMV LTSNNIALTP REPEATSWET TWGVESKSSD KEGTRAGEEE
RRPQQEDSLT EDQNKKLQEH LSLEKERKLK EEQQYQEEQE QKQRQYQEER ELRRRQAEAE
AEERARLGEE LKHQAERERE TSVKIYQYRR PVDSYDVSGR EEESSGLLPS DRNKSRSTTE
LDDYSSSKNG NNRYLDRIGN TSSLQKSSKK EQAPSGAELE RQQILQEMRK RTSLHNDNSW
IRQRSSSVNK EPICLPGIMR RGESLDNLDS PRSNSRRQSP WHNQSTGVYA SSSVQDFSRP
PPQLLSTSNR AYMRNPSSGV PPPSSGSGKT PSAPSPPSRS QSPSTTQSGS QLRNRSVSGK
RVCSYCNNIL GKGAAMIIES LGLCYHLHCF KCVACERDLG GSASGAEVRI RNNQLYCNDC
YLRFKSGRPT AM
//
