ID A0A1S3WN26_ERIEU Unreviewed; 343 AA.
AC A0A1S3WN26;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Patr class I histocompatibility antigen, A-5 alpha chain isoform X1 {ECO:0000313|RefSeq:XP_016047687.1};
GN Name=LOC103121786 {ECO:0000313|RefSeq:XP_016047687.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016047687.1};
RN [1] {ECO:0000313|RefSeq:XP_016047687.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|RuleBase:RU004439}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016047687.1; XM_016192201.1.
DR AlphaFoldDB; A0A1S3WN26; -.
DR GeneID; 103121786; -.
DR eggNOG; ENOG502QZ0U; Eukaryota.
DR InParanoid; A0A1S3WN26; -.
DR OrthoDB; 3840485at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd07698; IgC1_MHC_I_alpha3; 1.
DR CDD; cd12087; TM_EGFR-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675:SF250; HISTOCOMPATIBILITY 2, T REGION LOCUS 24; 1.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..343
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010259295"
FT TRANSMEM 314..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 215..293
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 343 AA; 39787 MW; 190EE863C2F9CE80 CRC64;
MLFLLILLFS FLRFPVETGA RSHSLQYFYS AVSEPVPGVP AFSAFGYVDD QRFIHYDSVG
MKAKSHALWL KEGPSYFDDE TKIFTSRMKL FHLNLRNLQQ YYNQTITHSL NKALKQKQAD
AHTLQFTYGC ELLDNGSTIG YWRYGYDGDD YLNLDMNLLQ YIPLSPMAHY TKQKWEHNRK
DFIERDKIYL EKECILWLRR YLECGGESLN RTDPPKTHMT HRSISSHGVI LKCWALGFYP
AEITLIWQRD GEDLTQDTEF AETRPGGDET FQKWAAVVVP SGEEQRYTCH VQHEGLPEPI
ILRVEIPPPF TSSILNIIIG LVLFVVIGVV LIGIMVRRKK YLV
//
