ID A0A1S3WNL4_ERIEU Unreviewed; 369 AA.
AC A0A1S3WNL4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Doublesex- and mab-3-related transcription factor C2 {ECO:0000313|RefSeq:XP_016047968.1};
GN Name=DMRTC2 {ECO:0000313|RefSeq:XP_016047968.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016047968.1};
RN [1] {ECO:0000313|RefSeq:XP_016047968.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00070}.
CC -!- SIMILARITY: Belongs to the DMRT family.
CC {ECO:0000256|ARBA:ARBA00006834}.
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DR RefSeq; XP_016047968.1; XM_016192482.1.
DR AlphaFoldDB; A0A1S3WNL4; -.
DR CTD; 63946; -.
DR eggNOG; KOG3815; Eukaryota.
DR InParanoid; A0A1S3WNL4; -.
DR OrthoDB; 4029770at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.1040.10; DM DNA-binding domain; 1.
DR InterPro; IPR001275; DM_DNA-bd.
DR InterPro; IPR036407; DM_DNA-bd_sf.
DR InterPro; IPR026607; DMRT.
DR InterPro; IPR031577; DMRT-C1/C2_C.
DR PANTHER; PTHR12322; DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT; 1.
DR PANTHER; PTHR12322:SF15; DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR C2; 1.
DR Pfam; PF00751; DM; 1.
DR Pfam; PF15791; DMRT-like; 1.
DR SMART; SM00301; DM; 1.
DR SUPFAM; SSF82927; Cysteine-rich DNA binding domain, (DM domain); 1.
DR PROSITE; PS40000; DM_1; 1.
DR PROSITE; PS50809; DM_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00070};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00070};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00070}; Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00070}.
FT DOMAIN 42..89
FT /note="DM"
FT /evidence="ECO:0000259|PROSITE:PS50809"
FT DNA_BIND 42..89
FT /note="DM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00070"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 107..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 39014 MW; 3A6172B2463CCCD1 CRC64;
MEPSEKPAVH HCPSDSTTGG ETTAPQGMEL VPKRAVTRSP TCARCRNHGV TAHLKGHKRL
CLFQACECHK CVLILERRRV MAAQVALRRQ QEAQLKRHLA QGLIRKGAIP PKTPSRVKKG
TTRPGGPPGK ENRVTQTPHG AVPVTLTPPG KNSRAPLLLS HPTEALPLPW APVLPGPWTP
GHWLPPGLSV PPPVVCRLLC QETAVPLHPF PGFEPGTSLR LPTHGPLPTC PGSRPILTAP
LSGESQGASV LPRTCSTLIL QPCGPPDPLL LQPQVPAASR LAWTSLSSER QLQREAAEAL
VGLKDSSQAP RLTPSISPNP AWISLLHPCG PPAAAGGRGF QPVGPSLRPS PAASVALHIG
RLGSISLLT
//
