GenomeNet

Database: UniProt
Entry: A0A1S3WR76_ERIEU
LinkDB: A0A1S3WR76_ERIEU
Original site: A0A1S3WR76_ERIEU 
ID   A0A1S3WR76_ERIEU        Unreviewed;      4561 AA.
AC   A0A1S3WR76;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   08-MAY-2019, entry version 14.
DE   SubName: Full=prolow-density lipoprotein receptor-related protein 1 isoform X1 {ECO:0000313|RefSeq:XP_016048840.1};
GN   Name=LRP1 {ECO:0000313|RefSeq:XP_016048840.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae;
OC   Erinaceinae; Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016048840.1};
RN   [1] {ECO:0000313|RefSeq:XP_016048840.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR   RefSeq; XP_016048840.1; XM_016193354.1.
DR   GeneID; 103124251; -.
DR   CTD; 4035; -.
DR   OrthoDB; 1606at2759; -.
DR   Proteomes; UP000079721; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00112; LDLa; 31.
DR   Gene3D; 2.120.10.30; -; 8.
DR   Gene3D; 4.10.400.10; -; 29.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR026823; cEGF.
DR   InterPro; IPR032485; DUF5050.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR   InterPro; IPR018097; EGF_Ca-bd_CS.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR036055; LDL_receptor-like_sf.
DR   InterPro; IPR023415; LDLR_class-A_CS.
DR   InterPro; IPR000033; LDLR_classB_rpt.
DR   InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR   Pfam; PF12662; cEGF; 1.
DR   Pfam; PF16472; DUF5050; 1.
DR   Pfam; PF07645; EGF_CA; 2.
DR   Pfam; PF00057; Ldl_recept_a; 29.
DR   Pfam; PF00058; Ldl_recept_b; 12.
DR   PRINTS; PR00261; LDLRECEPTOR.
DR   SMART; SM00181; EGF; 25.
DR   SMART; SM00179; EGF_CA; 6.
DR   SMART; SM00192; LDLa; 31.
DR   SMART; SM00135; LY; 35.
DR   SUPFAM; SSF57184; SSF57184; 4.
DR   SUPFAM; SSF57424; SSF57424; 30.
DR   PROSITE; PS00010; ASX_HYDROXYL; 1.
DR   PROSITE; PS00022; EGF_1; 3.
DR   PROSITE; PS01186; EGF_2; 2.
DR   PROSITE; PS50026; EGF_3; 6.
DR   PROSITE; PS01187; EGF_CA; 2.
DR   PROSITE; PS01209; LDLRA_1; 15.
DR   PROSITE; PS50068; LDLRA_2; 31.
DR   PROSITE; PS51120; LDLRB; 34.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000079721};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00124,
KW   ECO:0000256|SAAS:SAAS00601599};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076,
KW   ECO:0000256|SAAS:SAAS00438935};
KW   Lipoprotein {ECO:0000313|RefSeq:XP_016048840.1};
KW   Membrane {ECO:0000256|SAAS:SAAS00998125, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_016048840.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Repeat {ECO:0000256|SAAS:SAAS00594563};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00270323,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00270261,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20   4561       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5010190001.
FT   TRANSMEM   4441   4461       Helical. {ECO:0000256|SAM:Phobius}.
FT   REPEAT      292    334       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      335    378       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      379    422       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      571    613       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      614    659       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      660    710       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      711    754       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1326   1372       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1373   1415       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1416   1462       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1463   1507       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1508   1548       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1644   1686       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1687   1730       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1731   1770       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1771   1815       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1951   1993       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     1994   2036       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2037   2080       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2081   2124       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2270   2311       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2312   2360       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2361   2405       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2406   2448       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     2449   2490       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   DOMAIN     2999   3034       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   REPEAT     3086   3130       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     3131   3173       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     3174   3217       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     3218   3260       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     3261   3301       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     3929   3941       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     3987   4029       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     4030   4073       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT     4074   4118       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   DOMAIN     4213   4246       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     4249   4285       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     4286   4318       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     4321   4357       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DOMAIN     4392   4426       EGF-like. {ECO:0000259|PROSITE:PS50026}.
FT   DISULFID    854    866       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    861    879       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    895    907       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    902    920       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    936    948       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    943    961       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    984   1002       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID    996   1011       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   1032   1044       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   1039   1057       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   1099   1114       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   1142   1157       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2549   2567       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2583   2595       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2590   2608       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2602   2617       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2622   2634       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2629   2647       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2641   2656       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2690   2705       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2713   2725       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2720   2738       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2732   2747       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2751   2763       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2758   2776       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2835   2847       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2842   2860       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2875   2887       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2929   2947       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   2941   2956       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3003   3013       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   3351   3363       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3358   3376       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3391   3403       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3398   3416       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3410   3425       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3450   3465       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3553   3565       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3560   3578       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3572   3587       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3592   3604       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3599   3617       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3611   3626       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3630   3642       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3637   3655       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3649   3664       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3671   3683       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3678   3696       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3733   3748       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3766   3784       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   3778   3793       {ECO:0000256|PROSITE-ProRule:PRU00124}.
FT   DISULFID   4217   4227       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4253   4263       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4275   4284       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4289   4299       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4325   4335       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4347   4356       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4394   4404       {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT   DISULFID   4416   4425       {ECO:0000256|PROSITE-ProRule:PRU00076}.
SQ   SEQUENCE   4561 AA;  506604 MW;  3F788260677FA93E CRC64;
     MLTPPPLLLL PLLSALVAAA IDAPKTCSPK QFACRDQVTC ISKGWRCDGE RDCPDGSDEA
     PEICPQSKAQ RCQPNEHNCL GTELCIHMSH LCNGVQDCMD GSDEGAHCRE LRGNCSQLGC
     QHHCVPTLSG PACYCNNSFQ LQADGKTCKD FDECSVYGTC SQLCTNTDGS FLCGCVEGYL
     LQPDNRSCKA KNEPVDRPPV LLIANSQNIL ATYLSGAQVS TITPTSTRQT TAMDFSYANE
     TVCWVHVGDS AAQTQLKCAR MPGLKGFVDE HTINISLSLH HVEQMAIDWL TGNFYFVDDI
     DDRIFVCNRN GDTCVTLLDL ELYNPKGIAL DPAMGKVFFT DYGQIPKVER CDMDGQNRTK
     LVDSKIVFPH GITLDLVSRL VYWADAYLDY IEVVDYEGKG RQTIIQGILI EHLYGLTVFE
     NYLYATNSDN ANAQQKTSVI RVNRFNSTDY QVVTRVDKGG ALHIYHQRRQ PRVRSHACEN
     DQYGKPGGCS DICLLANSHK ARTCRCRSGF SLGSDGKSCK KPEHELFLVY GKGRPGIIRG
     MDMGAKVPDE HMIPIENLMN PRALDFHAET GFIYFADTTS YLIGRQKIDG TERETILKDG
     IHNVEGVAVD WMGNNLYWTD DGPKKTISVA RLEKAAQTRK TLIEGKMTHP RAIVVDPLNG
     WMYWTDWEED PKDSRRGRLE RAWMDGSHRD VFVTSKTVLW PNGLSLDIPA GRLYWVDAFY
     DRIETILLNG TDRKIVYEGP ELNHAFGLCH HGNYLFWTEY RSGSVYRLER GTEGAPPTVT
     LLRSERPPIF EIRMYDAQQQ QVGTNKCRVN NGGCSSLCLA TPGSRQCACA EDQVLDSDGV
     TCLANPSYVP PPQCQPGEFA CANSRCIQER WKCDGDNDCL DNSDEAPALC HQHTCPSDRF
     KCENNRCIPN RWLCDGDNDC GNSEDESNAT CSARTCPPNQ FSCASGRCIP ISWTCDLDDD
     CGDRSDESAS CAYPTCFPLT QFTCNNGRCI NINWRCDNEK DCGDGSDEKT CPEPADNDCG
     DNSDEAGCSH SCSSTQFKCN SGRCIPEHWT CDGDNDCGDY SDETHANCTN QATRPPGGCH
     TDEFQCRLDG LCIPLRWRCD GDTDCMDSSD EKSCEGVTHV CDPNVKFGCK DSARCISKAW
     VCDGDSDCED NSDEENCESL ACRPPSHPCA NNTSVCLPPD KLCDGNDDCG DGSDEGELCD
     QCSLNNGGCS HNCSVAPGEG IVCSCPLGME LGPDNHTCQI QSYCAKHLKC SQKCDQNKFS
     VKCSCYEGWV LEPDGESCRS LDPFKPFIIF SNRHEIRRID LHKGDYSVLV PGLRNTIALD
     FHLSQSALYW TDVVEDKIYR GKLLDNGALT SFEVVIQYGL ATPEGLAVDW IAGNIYWVES
     NLDQIEVAKL DGTLRTTLLA GDIEHPRAIA LDPRDGILFW TDWDASLPRI EAASMSGAGR
     RTIHRETGSG GWPNGLTVDY LEKRILWIDA RSDAIYSARY DGSGHMEVLR GHEFLSHPFA
     VTLYGGEVYW TDWRTNTLAK ANKWTGHNVT VVQRTNTQPF DLQVYHPSRQ PMAPNPCEAN
     GGRGPCSHLC LINYNRTVSC ACPHLMKLHK DNITCYEFKK FLLYARQMEI RGVDLDAPYY
     NYIISFTVPD IDNVTVLDYD AREQRVYWSD VRTQAIKRAF INGTGVETVV SADLPNAHGL
     AVDWVSRNLF WTSYDTNKKQ INVARLDGSF KNAVVQGLEQ PHGLVVHPLR GKLYWTDGDN
     ISMANMDGSN RTLLFSGQRG PVGLAIDFPE SKLYWISSGN HTINRCNLDG SGLEVIEAMR
     SQLGKATALA IMGDKLWWAD QVSEKMGTCN KADGSGAVVL RNSTTLVMHM KVYDESIQLG
     HEGTNPCSVN NGDCSQLCLP TSESTRACMC TAGYSLRSGQ QACEGVGSFL LYSVHEGIRG
     IPLDPNDKSD ALVPVSGTSL AVGIDFHAEN DTIYWVDMGL STISRAKRDQ TWREDVVTNG
     IGRVEGIAVD WIAGNIYWTD QGFDVIEVAR LNGSFRYVII SQGLDKPRAI TVHPEKGYLF
     WTEWGQYPRI ERSRLDGSER VVLVNVSISW PNGISVDYQD GKLYWCDARM DKIERIDLET
     GENREVVLSS NNMDMFSVSV FEDFIYWSDR THANGSIKRG SKDNATDSVP LRTGIGVQLK
     DIKVFNRDRQ KGTNVCAVAN GGCQQLCLYR GGGRRACACA HGMLAEDGAS CREYAGYLLY
     SERTILKSIH LSDERNLNAP VQPFEDPDHM KNVIALAFDY RAGTAPGTPN RIFFSDIHFG
     NIQQINDDGS HRITIVENVG SVEGLAYHRG WDTLYWTSYT TSTITRHTVD QTRPGAFERE
     TVITMSGDDH PRAFVLDECQ NLMFWTNWNE QHPSIMRAAL SGANVLTLIE KDIRTPNGLA
     IDHRAEKLYF SDATLDKIER CEYDGSHRYV ILKSEPVHPF GLAVYGEHIF WTDWVRRAVQ
     RANKFMGSDM KLLRVDIPQQ PMGIIAVAND TNSCELSPCR INNGGCQDLC LLTHQGHVNC
     SCRGGRILQE DLTCRAVNST CRAQDEFECA NGECINFSLT CDGVSHCKDK SDEKPSYCNS
     RRCKKTFRQC NNGRCVSNML WCNGADDCGD GSDEIPCNKT ACGLGEFRCR DGTCIGNSSR
     CNQFVDCQDA SDEMNCSATD CSSYFRLGVK GVRFQPCEHT SLCYAPSWVC DGANDCGDYS
     DERDCPGVKR PRCPLNYFAC PSGRCIPMSW TCDKEDDCEH GEDETHCNKF CSEAQFECQN
     HRCISKQWLC DGTDDCGDGS DEAAHCEGKT CGPSSFSCPG THVCVPERWL CDGDKDCADG
     ADESVTAGCL YNSTCDEREF MCQNRQCIPK HFVCDHDRDC ADGSDESPEC EYPTCGPEEF
     RCANGRCLSS RQWECDGESD CHDQSDEAPK NPHCTSPEHK CNASSQFLCN SGRCVAETLL
     CNGLDDCGDG SDERGCHVNE CLSRKLSGCS QDCEDLKIGF KCRCRPGFRL KDDGRTCADV
     DECSTTFPCS QRCINTHGSY KCLCVEGYAP RGGDPHSCKA VTDEEPFLIF ANRYYLRKLN
     LDGSNYTLLK QGLNNAVALD FDYREQMIYW TDVTTQGSMI RRMHLNGSNV QVLHRTGLSN
     PDGLAVDWVG GNLYWCDKGR DTIEVSKLNG AYRTVLVSSG LREPRALVVD VQNGYLYWTD
     WGDHSLIGRI GMDGSGRSVI VDTKITWPNG LTLDYVTERI YWADAREDYI EFASLDGTNR
     HVVLSQDIPH IFALTLFEDY VYWTDWETKS INRAHKTTGA NKTLLISTLH RPMDLHVFHA
     LRQPDVPNHP CKINNGDCSN LCLLSPGGSH KCACPTNFYL GGDGRTCVSN CTASQFVCKN
     DKCIPFWWKC DTEDDCGDHS DEPPDCPEFK CRPGQFQCST GICTNPAFIC DGDNDCQDNS
     DEANCDIHVC LPSQFKCTNT NRCIPGIFRC NGQDNCGDGE DERDCPEVTC APNQFQCSIT
     KRCIPRVWVC DRDNDCVDGS DEPANCTQMT CGVDEFRCKD SGRCIPARWK CDGEDDCGDG
     SDEPKEECDE RTCEPYQFRC KNNRCVPGRW QCDYDNDCGD NSDEESCTPR PCSESEFSCA
     NGRCIAGRWK CDGDHDCADG SDEKDCTPRC DMDQFQCKSG HCIPLRWRCD ADADCMDGSD
     EEACSTGVRT CPLDEFQCNN TLCKPLAWKC DGEDDCGDNS DENPEECARF VCPPNRPFRC
     KNDRVCLWIG RQCDGTDNCG DGTDEEDCEP PTPQSAHCKD KKEFLCRDQR CLPSSLRCNM
     FDDCGDGSDE EDCSIDPKMT SCATNTSLCG DEERCVRTEK AAYCACRPGF HTVPGHSGCQ
     DINECLRFGA CSQLCNNTKG SHLCSCARNF MKTHNTCKAE GSEYQVLYIA DDNEIRSLFP
     SHPHSAYEQA FQGDESVRID AMDVHVKAGR VYWTNWHTGT ISYRSLPPAA PPTTSNRHRR
     QIDRGVTHLN ISGLKMPRGI AIDWVAGNVY WTDSGRDVIE VAQMKGENRK TLISGMIDEP
     HAIVVDPLRG TMYWSDWGNH PKIETAAMDG TLRETLVQDS IQWPTGLAVD YHNERLYWAD
     AKLSVIGSIR LNGTDPIVAA DSKRGLSHPF SIDVFEDYIY GVTYINNRVF KIHKFGQSPL
     VNLTGGLSHA SDVVLYHQHK QPEVTNPCDR KKCEWLCLLS PSGPVCTCPN GKRLDNGTCV
     AVPSPTPPPD APRPGTCNLQ CFNGGSCFLN ARRQPKCRCQ PRYTGDKCEL DQCWEYCRNG
     GTCAASPSGM PTCRCPTGFT GPKCTQQVCA GYCANNSTCT VNQGNQPQCR CLPGFLGDRC
     QYRQCSDYCE NLGTCQMAAD GTRQCRCTAY FEGPRCEVNK CSRCLDGTCA VNKQSGDVTC
     NCTDGRVAPS CLSCLGHCSN GGSCTMNSKM MPECQCPPHM SGPRCEDPVV SQQQPAHMAS
     ILIPLLLLLL VLLIAGTVFW YKRRVRGAKG FQHQRMTNGA MNVEIGNPTY KMYEGGEPDD
     VGGLLDADFA LDPDKPTNFT NPVYATLYMG GHGSRHSLAS TDEKRELLGR GPEDEIGDPL
     A
//
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