ID A0A1S3WV99_ERIEU Unreviewed; 249 AA.
AC A0A1S3WV99;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transcription factor Spi-C {ECO:0000313|RefSeq:XP_016050245.1};
GN Name=SPIC {ECO:0000313|RefSeq:XP_016050245.1};
OS Erinaceus europaeus (Western European hedgehog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC Erinaceus.
OX NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016050245.1};
RN [1] {ECO:0000313|RefSeq:XP_016050245.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016050245.1; XM_016194759.1.
DR AlphaFoldDB; A0A1S3WV99; -.
DR STRING; 9365.ENSEEUP00000011351; -.
DR CTD; 121599; -.
DR eggNOG; KOG3805; Eukaryota.
DR InParanoid; A0A1S3WV99; -.
DR OrthoDB; 3980839at2759; -.
DR Proteomes; UP000079721; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF17; TRANSCRIPTION FACTOR SPI-C; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000079721}.
FT DOMAIN 112..195
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
SQ SEQUENCE 249 AA; 28722 MW; 043F050D51D6EF33 CRC64;
MEAGVEQDKL GQAFEDAFEI MRDNSTGDGS YPPDYKNYLA FINHCSHVRG TSSYYTMLPP
EEPVSNWRAV VNSATDFYLG GDIHQSLQHI SENQLAQPVV SQQKGGKGRK KLRLFEYLYE
SLCNPEMTSC IQWVDKSKGI FQFVSKNKEK LAQLWGKRKG NRKTMTYQKM ARALRNYGRT
GEITKIRRKL TYQFSESILQ RLSPSCFLDK EFFCSQYAQP NQDYFSLSNW NANYNCVAAS
YHESICPHC
//
