ID   A0A1S3WVM5_ERIEU        Unreviewed;       500 AA.
AC   A0A1S3WVM5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Double-stranded RNA-binding protein Staufen homolog 1 isoform X5 {ECO:0000313|RefSeq:XP_016050420.1, ECO:0000313|RefSeq:XP_016050421.1};
GN   Name=STAU1 {ECO:0000313|RefSeq:XP_016050420.1,
GN   ECO:0000313|RefSeq:XP_016050421.1, ECO:0000313|RefSeq:XP_016050422.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016050421.1};
RN   [1] {ECO:0000313|RefSeq:XP_016050420.1, ECO:0000313|RefSeq:XP_016050421.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_016050420.1; XM_016194934.1.
DR   RefSeq; XP_016050421.1; XM_016194935.1.
DR   RefSeq; XP_016050422.1; XM_016194936.1.
DR   GeneID; 103127507; -.
DR   CTD; 6780; -.
DR   OrthoDB; 2882160at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd19885; DSRM_STAU1_rpt4; 1.
DR   CDD; cd19887; DSRM_STAU1_rpt5; 1.
DR   Gene3D; 3.30.160.20; -; 4.
DR   Gene3D; 6.10.250.1360; -; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR032478; Staufen_C.
DR   PANTHER; PTHR46054:SF2; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1; 1.
DR   PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR   Pfam; PF00035; dsrm; 3.
DR   Pfam; PF16482; Staufen_C; 1.
DR   SMART; SM00358; DSRM; 3.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 3.
DR   PROSITE; PS50137; DS_RBD; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00266}.
FT   DOMAIN          46..81
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          103..176
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          209..277
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   REGION          81..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          283..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..101
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..305
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   500 AA;  55535 MW;  B323661D476A7539 CRC64;
     MKLGKKPMYK PVDPYSRMQS TYNYNMRGGA YPPRYFYPFP VPPLLYQVEL SVGGQQFNGK
     GKTRQAAKHD AAAKALRILQ NEPPPDRLEM NGRESEEENL NKSEISQVFE IALKRNLPVN
     FESFPLKQVA RESGPPHMKS FLTRVSVGEF VGEGEGKSKK ISKKNAAIAV LEELKKLPPL
     PTAERVKPRI KKKTKSIVRN SPEYGQGMNP ISRLAQIQQA KKEKEPEYML LTERGLPRRR
     EFVMQVKVGN HTAEGSGTNK KVAKRNAAEN MLEILGFKVP QAQPTKPALK SEEKTPLKKS
     GDGRKVTFFE PGSGDENGTS NKEDEFRMPY LSHQQLPAGI LPMVPEVAQA VGVSQGHHTK
     EFTRAAPNPA KATVTAMIAR ELLYGGTSPT AETILKSNIS SGHVPHGPLT RPSEQLDYLS
     RVQGFQVEYK DFPKNNKNEF VSLINCSSQP PLISHGIGKD MESCHDMAAL NILKLLSELD
     QQSTEMPRTG NGPMSMCGRC
//