ID   A0A1S3WXB4_ERIEU        Unreviewed;       946 AA.
AC   A0A1S3WXB4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Cilia- and flagella-associated protein 70 isoform X2 {ECO:0000313|RefSeq:XP_016050819.1};
GN   Name=CFAP70 {ECO:0000313|RefSeq:XP_016050819.1};
OS   Erinaceus europaeus (Western European hedgehog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae;
OC   Erinaceus.
OX   NCBI_TaxID=9365 {ECO:0000313|Proteomes:UP000079721, ECO:0000313|RefSeq:XP_016050819.1};
RN   [1] {ECO:0000313|RefSeq:XP_016050819.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_016050819.1; XM_016195333.1.
DR   AlphaFoldDB; A0A1S3WXB4; -.
DR   CTD; 118491; -.
DR   OrthoDB; 55813at2759; -.
DR   Proteomes; UP000079721; Unplaced.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR44314; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70; 1.
DR   PANTHER; PTHR44314:SF1; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70; 1.
DR   Pfam; PF13181; TPR_8; 3.
DR   SMART; SM00028; TPR; 8.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Cell projection {ECO:0000313|RefSeq:XP_016050819.1};
KW   Cilium {ECO:0000313|RefSeq:XP_016050819.1};
KW   Flagellum {ECO:0000313|RefSeq:XP_016050819.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000079721};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   REPEAT          825..858
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          615..643
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        629..643
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   946 AA;  107459 MW;  9B268313C72C4F31 CRC64;
     MTEVLPKEKK QKDEKTLVLA QAVVDLLPLI EGETSFETMV PLHPVPGSPL ESLRSTAKCC
     LEVKVFVAEA LLTSSQILGG NLLKVTLEAA YSVPESFVPI GSLQNYMVGL QVPSAGEKDY
     PIFFKNGTVK LGGEREPVPR PKKWPIANIL APGANNIPDA FIVGGPYEEE EGELNRPEDR
     EFRNQAECIK KRIVWDLESR CYLNPHAVVS FQKRIADCRL WPVEITRVPL TPAPKGKTTK
     FDKIDDENQL SFHGVAYVNM VPLLYPGVKR IRGAFHVHPY LDSIVYEKQY VEAGTYIVLE
     IQLDKALVPK RLPEELAKRV KEMIPPRPPL TRRTGGAQKA VSDYHAQIKN ISRAILDEYH
     RMFGKQMAST GNDLDNETLD EQKCQLNYEL NYSGKYFAFK EQLKHAVVKI VREKYLKTTS
     FESQEELQAF ISELYVFLVD QMHVALNQTM SDDIQDAVST IYTSSEQLRF FAFEAEVNEN
     FDMARMYYEE RLVREPQNLE HWLDYGAFCL LTEDNIKAQE CFQKALSLNQ NHIHSLLLCG
     VLAVLMENYE QAEIFFEDAT CLEPTNVVAW TLLGLYYEIQ NNDIRMEMAF HEASKQLQAR
     VLQAQVLKQK SNGTVEYEEG GNIESSPGPW RMPSASSTTA MKMEGSGGAT LSILDEFLEE
     SSKLQSESQE PLFTDPSVSQ KPSNQYIKDI LEKKDTSKCQ DSSVWLHLNS TNISQSHVTI
     FMETIRFLMK VNAVQYVHRV LAHELLCPQG GPSCEYYLVL AQTHLLKKDF AKAEEYLQQA
     AQMDYLNPNV WGVKGHLYFL SGNHAEAKAC YERTISFVTD ASEMHFIFLR LGLIYLEEKE
     YEKAKKTYLQ ACKRSPSCLT WLGLGIACYR LEELTEAEDA LSEANALNNC NAEVWAYLSL
     VSLKAKRQLE AEQAYKYTMK LKLKDEALLA EIHMVQETVG FGNPSF
//