ID A0A1S3X226_TOBAC Unreviewed; 222 AA.
AC A0A1S3X226;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Mitotic spindle checkpoint protein MAD2 isoform X1 {ECO:0000313|RefSeq:XP_016434045.1};
GN Name=LOC107760504 {ECO:0000313|RefSeq:XP_016434045.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016434045.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016434045.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
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DR RefSeq; XP_016434045.1; XM_016578559.1.
DR AlphaFoldDB; A0A1S3X226; -.
DR SMR; A0A1S3X226; -.
DR STRING; 4097.A0A1S3X226; -.
DR PaxDb; 4097-A0A1S3X226; -.
DR GeneID; 107760504; -.
DR KEGG; nta:107760504; -.
DR OrthoDB; 5474106at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000776; C:kinetochore; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IBA:GO_Central.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF11; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 14..197
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
SQ SEQUENCE 222 AA; 25047 MW; 694EE2B180A05F86 CRC64;
MASRTATKDI ITLRGSAAIV AEFFGYAANS ILYNRGVYPE ESFAKVKKYG LQMLLTQDEG
VKTFISNLTA QLSEWLEAGK LQRMVLVIMS KASGEVLERW NFSVETDSEV VEKGVSREKS
DKEIMREIQA IMRQIISSVT FLPCLEEPCV FDVLAYTDTD VAVPFTWIES DPKLIANPHM
VKLHSFDTKI HKGKPTLSPS SIRYVVFFPL SRLSKRGAHF KE
//
