ID A0A1S3X2X9_TOBAC Unreviewed; 579 AA.
AC A0A1S3X2X9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN Name=LOC107760752 {ECO:0000313|RefSeq:XP_016434340.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016434340.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016434340.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR RefSeq; XP_016434340.1; XM_016578854.1.
DR AlphaFoldDB; A0A1S3X2X9; -.
DR SMR; A0A1S3X2X9; -.
DR STRING; 4097.A0A1S3X2X9; -.
DR PaxDb; 4097-A0A1S3X2X9; -.
DR GeneID; 107760752; -.
DR KEGG; nta:107760752; -.
DR OMA; HMGKGSK; -.
DR OrthoDB; 1699at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR CDD; cd17039; Ubl_ubiquitin_like; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR044571; P4KG1-8.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR019956; Ubiquitin_dom.
DR PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR PANTHER; PTHR45800:SF4; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA 3; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00240; ubiquitin; 2.
DR PRINTS; PR00348; UBIQUITIN.
DR SMART; SM00213; UBQ; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 34..105
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 110..187
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT DOMAIN 263..561
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 579 AA; 64071 MW; 3C4B0950D16BFADA CRC64;
MSIASVALSP VFEDNLNLAG CLSAQHGSWS NDSILIFLTV GGSVIPLRVK ESDSIASVKL
RIQTYKGFFV KKQKLVFEGR ELARNNSCVR DYGVADCNIL HLVLRLSDLQ AITVRTVCGQ
EFEFHVERKR NVGYVKQQIA KKRKGFCNLK EQELIFDGEE LEDKRLIDDI CKSNDAVLHL
LVRKSAKVQA RAVQKDFEVS IVASSDENGA DAVEKLQESI QVVPLNTVPR SFILEPLIVN
PKITLSPVVK QLIGSTFDGI EMGHQPIRSS EGSGGAYFML DSCGQNYVSV FKPIDEEPMA
ANNPRGLPLS VDGEGLKKGT RVGEGALREV AAYILDHPKS GPRSTCSDEK GFAGVPPTIM
VKCLHTGFNY VEGCEYSSGC LKIGSLQMFM KNCGSCEDLG PRAFPVDDVH RISVLDIRLA
NADRHAGNIL VQKDDKDGQL VLIPIDHGYC LPENFEDCTF DWLYWPQAQQ PYSAETIAYI
NSLDAEKDIE LLKFHGWTLS LACARVLRIS SMLLKKGAKR GLTPFAIGRI MCRETLKKES
VIEQIVEEAQ EGVLPETSEA AFLQSISMVM DRHLDDLIK
//
