ID   A0A1S3X3G5_TOBAC        Unreviewed;       814 AA.
AC   A0A1S3X3G5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Lysine-specific demethylase JMJ25-like isoform X5 {ECO:0000313|RefSeq:XP_016434524.1, ECO:0000313|RefSeq:XP_016434525.1};
GN   Name=LOC107760914 {ECO:0000313|RefSeq:XP_016434524.1,
GN   ECO:0000313|RefSeq:XP_016434525.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016434525.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016434524.1, ECO:0000313|RefSeq:XP_016434525.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_016434524.1; XM_016579038.1.
DR   RefSeq; XP_016434525.1; XM_016579039.1.
DR   GeneID; 107760914; -.
DR   OrthoDB; 774188at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR   Gene3D; 2.60.120.650; Cupin; 1.
DR   InterPro; IPR045109; JHDM2-like.
DR   InterPro; IPR003347; JmjC_dom.
DR   InterPro; IPR018866; Znf-4CXXC_R1.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR   PANTHER; PTHR12549:SF49; LYSINE-SPECIFIC DEMETHYLASE JMJ25-LIKE ISOFORM X1; 1.
DR   Pfam; PF02373; JmjC; 1.
DR   Pfam; PF10497; zf-4CXXC_R1; 1.
DR   SMART; SM00558; JmjC; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS51184; JMJC; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   DOMAIN          73..120
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          510..814
FT                   /note="JmjC"
FT                   /evidence="ECO:0000259|PROSITE:PS51184"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..37
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   814 AA;  93261 MW;  EECD50440F61A4F5 CRC64;
     MQNKRRKSEE KDIPVVMIES SSEEEEAEKD DNYVGDSDED SCDHSMEKMK KRKRKVGSDK
     TIGGNGKMES KMCHQCQRND KGRVVCCSKC KAKRYCVPCM TRWYPGMPEE AFLKACPVCR
     HNCNCIACLR LDGLAKHLMN VEMKFSDEEK LEYSKHILRA LLPALEQFNT EQMIEKEIEC
     HIKGLPDSEV NIRKAKYEKD ERIYCNYCSA SIVDLHRSCS SCSYELCLTC CKELRNGNLQ
     ADASEVKVQY IDYGPGYLHG KHCSITPANN GTCTETTEFK LRDQIKVAVT SKWKPKENGA
     IPCPPKDMGG CSKGTLNLRC IFSENWISQL LLKAKEIAQK CKLKEMHNDS ELHCSCPKYK
     GVNDTSGGKL RKAAARENSD DNYVFCPAVG DAQLANLKHF QYHLFKGEPI IVTNVLDSAL
     GLSWEPMVMW RACRQSKKTT DVLNCLNWCE LEMNIHQFFK GYMEGRFDSY GWPQLLKLND
     WPPSGLFDER LPRHGAEFSC CLPFKEYTHP QYGYLNLALR LPDNCLKPDL GPKAYIAYGF
     PTELGRGDSV TKLHYVVSDT VNVLMHTQAM VPTVEQLSAI ENLKQNHKAQ DQREFVTGAN
     RMPRRIKDSV PNVNGKSDLE GLNFSQDKQN CDSLKVENSN KAENMKYRQQ GLKVENSNKG
     ENKKNSQRVV KADCGTNKIG EKYQYREDSS LFGQNLSERF EEEDGGGALW DVFRRQDVPK
     LEEYLTKHFR EFRHIYGSPL PQVVHPIHDK TFYLSTEHKR RLKEEYGIEP WTFVQKLGEA
     VFIPAGCPHQ IRNLKFIFYS PASTSLLILY HLKM
//