ID A0A1S3X800_TOBAC Unreviewed; 1321 AA.
AC A0A1S3X800;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Disease resistance RPP13-like protein 1 {ECO:0000313|RefSeq:XP_016436017.1};
GN Name=LOC107762196 {ECO:0000313|RefSeq:XP_016436017.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016436017.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016436017.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR RefSeq; XP_016436017.1; XM_016580531.1.
DR PaxDb; 4097-A0A1S3X800; -.
DR GeneID; 107762196; -.
DR KEGG; nta:107762196; -.
DR OMA; CYAIIEL; -.
DR OrthoDB; 524180at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1237; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 11..103
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 184..402
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 127..154
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 717..746
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1321 AA; 150467 MW; 8153AC16416391ED CRC64;
MEIGLAVGGA FLSSALNVLF DRLAPQGELL KMFQRDKHDV RLLKKLRITL LGLQAVLCDA
ENKKASNQYV SQWLIELQDA VDSAENLMEE INYEVLRVKV EGQYQNLGET SNQQVSDLNL
CLSDEFFLNI KEKLEDAIET LEELEKQIGR LDLKAYLDSS KQETRKPSTS VVDESDIFGR
QNEIMELVDR LLSVDANGKN LTVIPIVGMA GVGKTTLAKA VYNDENKVKD HFNLKAWICV
SEPYDAFRIT KGLLQEIGSF DSMIDNNLNQ LQIKLKENLK GKKFLIVLDD IWNENYNEWD
DLRNLFVQGE KGSKIVVTTR KESIALMMGS GPIRVGTLSG EVSWDLFERH ALENRDPKGL
SKLRHVGIQI ANKCNGLPLA LKTLAGLLRS KSDVEEWRHI LRSETWELPN CPNGILPALM
LSYNDLPAYL KRCFSYCAIF PKDYSFCKEQ VIHLWIANGL IQRFHKDENI EDSSIQCFLE
LKSRSLFERV PNSTQRSNIE KYQMHDLVND LAQIASAKLC IRLEDNEPSH TLERSRHLSY
SMDHGDLEKL KPLYKLEQLR TLLPLSIQPH SSIKLSERVL HNILPTLKSL RALSLSRYAI
KELPSVLFIK LKLLRFLDLS RTMIKMLPDS VCLLYNLETL LLSSCDYLIE LPLQLENLIS
LRHLDISGSS LLKLSLHPSK LKSLHVLRGA RFLLGGYSGS IIGELGELHN LYGSVSVLAL
QNVVDRKEAQ KANMRKKEYI EELSLEWSES IADNSQIERD ILDDLQPDTN IKELQITGYR
GTKFPNWLAY PSFLKLVKLS LIKCKDCDSL PALGQISSLK FLTIKGMHRV LEVTEEFYGT
SFFNKPFNSL EKLEFSEMLE WKQWHLLGNG EFPILRDLSI ENCPKLMGKL PENLSSLIEL
NISKCPQLIL ETPVQLPYLK MFRVVGSPKL GVLFNRAELF TSQLQGLKQI AELYIIDCHA
LTSLPISSLP DTLKRIWMYR CGKLKLESPV SEMITSGHNM FLESFRLHRC HSIDDILPEL
VPRAHSLSVD GCPRLTRLLI PTATEVLGIY KCENLEILSV ARGTQMTSLH TLVIRDCQKL
KSMPERMQEL LPFLKKLELH NCPEIKSFPE EGLPFSLGVL VIDDCKKLVH GRKQWHLQRL
PYLTELTIFH DGSDEEILAD ENWELPSSIR ILMIYNLKTL SSQVLKNLTS LIHLLIGSLP
QVWSLLEEGL PSSLCYLSLY DHPELHSLPT EGLRSLTSLQ CLRIDKCPNL HSLPELALPS
SLIELRIDRC PNLKPLPLKG MPPSIFELSI SECPLRKPRL EFEKGGYFAH ISEIYIDGEC
L
//
