ID A0A1S3XA74_TOBAC Unreviewed; 428 AA.
AC A0A1S3XA74;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Translation initiation factor eIF2B subunit beta {ECO:0000256|ARBA:ARBA00044122};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit beta {ECO:0000256|ARBA:ARBA00044228};
GN Name=LOC107762934 {ECO:0000313|RefSeq:XP_016436810.1,
GN ECO:0000313|RefSeq:XP_016436811.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016436811.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016436810.1, ECO:0000313|RefSeq:XP_016436811.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR RefSeq; XP_016436810.1; XM_016581324.1.
DR RefSeq; XP_016436811.1; XM_016581325.1.
DR STRING; 4097.A0A1S3XA74; -.
DR PaxDb; 4097-A0A1S3XA74; -.
DR GeneID; 107762934; -.
DR OMA; ISGCHEQ; -.
DR OrthoDB; 169494at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; IBA:GO_Central.
DR GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR GO; GO:0006413; P:translational initiation; IBA:GO_Central.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR45859; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR PANTHER; PTHR45859:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|RefSeq:XP_016436810.1,
KW ECO:0000313|RefSeq:XP_016436811.1};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_016436810.1,
KW ECO:0000313|RefSeq:XP_016436811.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT REGION 143..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 46279 MW; 0A3E771E81EE9082 CRC64;
MPDMNTLVND FIIKLKKRKI EGSKATAKLT AEVLRSCISQ QRLPHTNQAA ALIDAIRTIG
EKLIAANPVE LAVGNIVRRV LHIIREEDVS LTAAAVGGLA VLAGSDDEDD FKQDDHPDLS
AAAVAAASRS TLRPPSLQTL LEDIPQSTAA PHTSSSGGDS EGKSKSADKN TASRKLKHNI
IEAVNELIQD IATCHEQIAE QAVEHIHHNE VILTLGNSRT VMEFLCAAKE KKRSFRVFVA
EGAPRYQGHA LAKELVARGL QTTVITDSAI FAMISRVNMV VVGAHAVMAN GGVIAPVGMN
MVALAAQRHA VPFVVLAGTH KLCPLYPHNP EVLLNELKSP AELLDFGEFS DCLDFGSSSG
SPLLHVVNPA FDYVPPNLVS LFITDTGGHN PSYMYRLIAD YYSADDFVVK QSSISLNSIK
LRLFYTYY
//
