ID A0A1S3XC12_TOBAC Unreviewed; 612 AA.
AC A0A1S3XC12;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU366043};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU366043};
GN Name=LOC107763474 {ECO:0000313|RefSeq:XP_016437442.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016437442.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016437442.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU366043}; Single-
CC pass type II membrane protein {ECO:0000256|RuleBase:RU366043}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361, ECO:0000256|RuleBase:RU366043}.
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DR RefSeq; XP_016437442.1; XM_016581956.1.
DR AlphaFoldDB; A0A1S3XC12; -.
DR STRING; 4097.A0A1S3XC12; -.
DR PaxDb; 4097-A0A1S3XC12; -.
DR GeneID; 107763474; -.
DR KEGG; nta:107763474; -.
DR OrthoDB; 1202783at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004159; Put_SAM_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10108:SF1103; METHYLTRANSFERASE PMT9-RELATED; 1.
DR PANTHER; PTHR10108; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF03141; Methyltransf_29; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|RuleBase:RU366043};
KW Membrane {ECO:0000256|RuleBase:RU366043};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU366043};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Signal-anchor {ECO:0000256|RuleBase:RU366043};
KW Transferase {ECO:0000256|RuleBase:RU366043};
KW Transmembrane {ECO:0000256|RuleBase:RU366043};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366043}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366043"
SQ SEQUENCE 612 AA; 70395 MW; 817DEDFE57411B4F CRC64;
MKQKKELLHR PKLLKYAIFG MIVFLGLICL YNCSFIAPGL PRARDPFAFE DGSDRVTGMS
HYRRVDMDFD DQELSLEVPK SIPVCDTRYS ELIPCLDRNL IYQLRLRLNL TVMEHYERHC
PPPQRRYNCL IPPPAGYKIP IRWPASRDQV WKANIPHTHL AQEKSDQNWM VVDGDKIKFP
GGGTHFHYGA DKYIAAIAGM LKFPGEKLSN GGNIRNVLDV GCGVASFGAY LLSHDIIAMS
LAPNDVHENQ IQFALERGIP SALGVLGTKR LPYPSRSFEL AHCSRCRIDW LQRDGILLLE
LDRLLRPGGY FVYSSPEAYA HDAENRRIWN AMYDLLRRMC WRVVSRRDQT VIWAKPLSNS
CYMKRTPGTQ PPLCMSGDEP DEAWNVPMKA CITLYSPKVH KEKGTGLLPW PKRLTAPPPR
LEEIGVTLEE FHKDTSVWHD RVIDYWKQMK SLIQKNSFRN VMDMNSNLGG FAAALKDKDI
WVMNVAPPNL SSRMKIIYDR GLIGTVHDWC ESFSTYPRTY DLLHAWMILS ETEERGCSIE
DLLIEMDRML RPEGVVIIRD NPHIINSVRK LLTALKWDGW SSEVEPRTDA LSLSEEKVLI
ARKKLWQEKF TI
//
