ID A0A1S3XN12_TOBAC Unreviewed; 2333 AA.
AC A0A1S3XN12;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC107766927 {ECO:0000313|RefSeq:XP_016441313.1};
GN Name=LOC107766927 {ECO:0000313|RefSeq:XP_016441313.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016441313.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016441313.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016441313.1; XM_016585827.1.
DR SMR; A0A1S3XN12; -.
DR STRING; 4097.A0A1S3XN12; -.
DR PaxDb; 4097-A0A1S3XN12; -.
DR GeneID; 107766927; -.
DR KEGG; nta:107766927; -.
DR OMA; HSEDIHG; -.
DR OrthoDB; 450776at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd18042; DEXXQc_SETX; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF490; P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 1454..1827
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1835..2040
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 2163..2254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2295..2333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1716..1743
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2163..2189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2215..2254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2295..2316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2333 AA; 260975 MW; 985B1D12A2EF4BD0 CRC64;
MTAEGIGRMS KKVVTRRELL DRWRGIEDDD DIASVDLLKR HRFRLLKEEW FSDAFNYLIF
LPEENHIWCG SWDLMGPLLE TFYNYFKDDR SDSPLKLLLD RTSREMRQCT QCICQYHQAQ
ELYSTEYDSS SIGPLLEVLD TLDEERISQH LKEINNRIRC GEYDIVHDSG EIVSVMFEVL
MFPILLDDSY LAIEFETFID AIDKSHELTL GGHQQYPGVY ALLFHKGRRA RSIGLRLAGR
MSKLRQSADL DALQPLLKKY ISYLAADVLS LSSQNPRPRV ELDRVTVWLG IKALLGFLEP
PAFEEGILDR YPIFLSVVLN HISDDSPEFS CAVNCLRLLF EMLGYKLWLK TSLSPSVMRN
TLLGQCFHTR NEKSNKEIFD LFQPFLQSLE ALQDGEHEKQ RRNLLYFLLH QVTVSSNFSL
LMRKKACQIA LLIVHRGYTM NPPSPPYECA HMWGPSLVSS LKDSSLHSSL RQPAFDVVQT
IIVSDAVALV TSILKYGLAS SDERCLPFQL DEEDGQENLF GCDFEENDDS CWKQFSCWKE
FSSQADISSD VCGDWMCIPM LWFEVLVEID PLVLPVSFAK AVFWALSRLS LLESVNDTDL
TPSLGHWLRT CASDISHVFN WKVPSGSNDG VEGVESKNSI KVSTKCIPLI RLFKRLTAHF
IIRMDQGELR KQWTWEPMMS DSLILLLVDP NDNARHVGRC ILEQVSNTRG LTSGLQFLCS
SPSSLSATFT GFRHALKLVQ LDCVLSEFQT LHHFFFVLCK LLKEGSSCTQ PLVRKSSEDS
SISKFSSQGG FLKQPVLQTQ TEHMDAHKSV VSFIVWEKFC CLLSEMAWIS VQKCLAAGKV
FIGQKPSQMT CIRLLETLPV VFRRLCNDPT TVLNIAVTQC LRNLIDWGHS PLAVVVRYWK
DALISLLILI KASCSGVPAS LAADIEKLIS CDNIPMNELT RQAARLSVSL VDGSSTDLKK
ASVVSKGLSG VESVLADNYL FETAKPFSGE VKKVHVPDLK TLVGEERVNL VVHSGDERET
DISASADINS CVSVNPKPVG HIAGRGLYSD PVKGIDSKKI SQPVDLCLDL DIPLELDALQ
AGKESSLVKS KAVEPKSKET DIKCRLNYTN LISKEDSSIA SQLHSALGSS SDGGVSIKEN
DGEGDRVMKT NNTVLKELVS ENKSDRELAF LTSARRQQSF SIKSSLSGPK RKVIQLSLPV
ENRSNVLRLD GVKRFKAVRL DDWYRPILEF DYFVTVGLKT AGEGKNDSLS NLKQVPVCFQ
SADDYVEIFR PLVLEEFKAQ LQSSFQEITS LEEMSCGSLS VMSVERIDDF HFIRCVHEDV
DSAGSKSCSE NDLILLTRQP LRNSSHDIHM VGKVEKREKD CKKRSSILLI RVYLQNRPHL
IRARKLLVER SKWCISRLMT ITSQVREFQA LSAIRGIPLL PVILNPSSYD LCKHHSESFN
KLSRPLQQVL KSAYNGSQLE AISAAIGPFD PKKEFQLSLI QGPPGTGKTR VIVAIVSALL
AFSQVDTRRS SSEGPKSTGM SCTASRQRIC QAAAVARAWQ DAALARQLNE DLENDKPMGN
SIKRRILICA QSNAAVDELV SRIISEGLYG SDGMMYKPYI VRVGNAKTVH ANSLPFFIDT
LVDHRIAEEK MNASDSKNDA DKDTLTFLRS NLEKLVDTIR CYEAKRASLR DGNSDSNCLL
EGDTDKADNA KELSDAEVEA KLRILYEKKK SIYMDLAAAQ AREKKANEEA KALRHKLRKA
ILKEAEIVVT TLSGCGGDLY GVCAASVSGQ RFSSSSEGVL FDAVVIDEAA QALEPASLIP
LQLLKSKGTR CVMVGDPKQL PATVLSNIAS KFSFQCSMFE RLQRAGYPVN MLTQQYRMHH
EICRFPSFHF YDGKLVNGDK LSSKVASFHG TKGLGPYVFF DVVDGKELHD KKSGTLSLYN
ECEADAAVEV LRFFKNRFPS EFVGGRIGII TPYRRQLSLL RSRFSSAFGS SITADMEFNT
VDGFQGREID IVILSTVRAL EACSTAAQVN AGRIGFVADV RRMNVALTRA KLSLWIMGNT
RTLQTNQSWA ALVKDAKERE LVMALKRPYN STFNSVDLEK HLTLDNPENC SRKLKHVKGN
EVTCKRADRQ NKNVKHVMER KRKNTSSGAP IDTLICADLS GKNVEGKQIA KDESSLLLKK
DLDNYDGKNT KHGENQSESS ESCEKISKKH RKERNAHGLR GKQCETLESN LGHSKKSGSD
NHKHSISVAS ERCQEPLVRD DKQRDTRGWK KPAKATLMQK DAEDGVGACN QVKKLNHTIS
ERKQQRDAVD ALLSSALISS NKSRSSLRSV PAKRMSSPNA SGPPIRPPKQ NKN
//
