ID A0A1S3XPU3_TOBAC Unreviewed; 392 AA.
AC A0A1S3XPU3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN Name=LOC107767270 {ECO:0000313|RefSeq:XP_016441677.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016441677.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016441677.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR RefSeq; XP_016441677.1; XM_016586191.1.
DR AlphaFoldDB; A0A1S3XPU3; -.
DR SMR; A0A1S3XPU3; -.
DR STRING; 4097.A0A1S3XPU3; -.
DR PaxDb; 4097-A0A1S3XPU3; -.
DR GeneID; 107767270; -.
DR KEGG; nta:107767270; -.
DR OMA; EMEDEIC; -.
DR OrthoDB; 459876at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR PANTHER; PTHR13832:SF589; PROTEIN PHOSPHATASE 2C 57; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 62..351
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 392 AA; 43029 MW; C3F06A5A28F59BC7 CRC64;
MALSSPYLQK VLLNRLCCNY GYKKNIIIKA GGGGRGGEGR GRCCSAIAIN APAPLTSVSG
IRWGSTLIQG PREEMEDDAV IVQSDDLDGF TYAAVFDGHA GFSSVKFLRE ELYKECITAL
QGGLLLEKRD LNAIQKALQE AFENADRKLL NWLESSGKED ESGSTATVLF VGNDTLIIAH
VGDSSVVLSR SGKMEVLTNA HRPYGSNKVS LQEIRRINEA GGWIVNGRIC GDISVSRAFG
DMRFKTKKNE MLEKGIEEGR WSEKFVSRIQ FKGDLVTASP DVLQVALGSD TEFVLLASDG
LWDYMKSAEV VDFVRNQLRE HGDVQVACEA LARTAMDRRT QDNVSIVIAD LGRTDWRNLP
VQKQNIVFEL GQALITISFV SLGIWLTTVI SP
//
