ID A0A1S3XVZ6_TOBAC Unreviewed; 1096 AA.
AC A0A1S3XVZ6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Probable LRR receptor-like serine/threonine-protein kinase At1g74360 {ECO:0000313|RefSeq:XP_016444116.1};
GN Name=LOC107769421 {ECO:0000313|RefSeq:XP_016444116.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016444116.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016444116.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_016444116.1; XM_016588630.1.
DR AlphaFoldDB; A0A1S3XVZ6; -.
DR SMR; A0A1S3XVZ6; -.
DR STRING; 4097.A0A1S3XVZ6; -.
DR PaxDb; 4097-A0A1S3XVZ6; -.
DR GeneID; 107769421; -.
DR KEGG; nta:107769421; -.
DR OMA; RGRYSEW; -.
DR OrthoDB; 471815at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48053; LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED; 1.
DR PANTHER; PTHR48053:SF172; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 6.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51450; LRR; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_016444116.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Receptor {ECO:0000313|RefSeq:XP_016444116.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1096
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010350019"
FT TRANSMEM 721..748
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 805..1080
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 834
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1096 AA; 120417 MW; FAF0C1AB932A9528 CRC64;
MSEEESDILL RLALFHFLLL ITSGRIVCGD SLETDKRVLL SFKSFLEEQN PINKGYKHTE
WNPTDSSPCN WPGILCDSGI NRVTEIHLSN NNLSGKFFDN FSAMTALTYI DLSTNTIGGA
IPADLGQCQN LRFLNLSHNI IDGGLNLTRL NNLQVLDLTM NRIHGEIKLT FPGICDSLVV
ANISYNNFTG EIGSTFDQCW NLKYLDLSYN NLTGELSLGF DKLMEFSVSN NKFTGSLPSL
FFTPNCSLQA LDLSENGFVG GFSKEISNCK NLEELNLFGN NFSGPIPREI GSVMSLQALY
LGSNNFSRDI PGSLLGLSNL VFLDLSRNNF RGEIQEIFGR FTQVRFLLLH GNSYTGGIVS
SGIPNLVNLS RLDLSNNQFS GPLPVELSKM EGLEFLILAY NQFNGSIPSE YGDIPTLQAL
DLSSNKLTGV IPPGLGKLNS LLWLMLANNS LVGGIPPELG NCSSLLWLNL ANNQLSGPIP
PQLARIGSNP MPTFLLNRKK DKVTAGSGEC FAMRRWIPAD YPPFSFVYPL LTRKNCRSLW
DKLLKGYGLF PVCEPGSNVR SNQISGYLQL SKNKFSGGIP PEIGSMLNFS MLHLGVNEFS
GTLPPEIGKM QLVVLNVSQN RISGEIPSQI GYIKCLLNLD LSYNNFSGLF PASFSNLTDL
SKFNISYNPY IYGSIPESGQ LTTFEKSSYL GDPLLRLPSF IDNSTDNAIN KGGSFKRTTK
IGAILVFLAL VLAFLVCGVM TLIVCLVLKS PIDTPGYLLE DSKGRHDLPS SSGASSPWLS
NDVKVIRLDT TSFTHSDILK ATGRFSNDRI IGKGGFGTVY RGILPDGREV AVKKLQREGF
EGEREFRAEM EVLSGNDFGW HPNLVTLYGW CLNGSEKLLV YEYMEGGSLD DIITDRTKFT
WKRRINVAID VARALVFLHH ECYPCIVHRD VKASNVLLDK DGRARVTDFG LARVMDAGDS
HISTMVAGTV GYVAPEYGQT WQATTKGDVY SYGVLAMELA TGRRAVDGGE ECLVEWARRV
MGDGRQGFTR AMIPVALLVS GLAEGAEELS GLLRIGIRCT ADNPHARPNM KEVLDMLITV
SRSQRSGSSH STSPSF
//
