ID A0A1S3XYB5_TOBAC Unreviewed; 375 AA.
AC A0A1S3XYB5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ribonuclease 3-like protein 2 {ECO:0000313|RefSeq:XP_016444707.1};
GN Name=LOC107769963 {ECO:0000313|RefSeq:XP_016444707.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016444707.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016444707.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016444707.1; XM_016589221.1.
DR AlphaFoldDB; A0A1S3XYB5; -.
DR SMR; A0A1S3XYB5; -.
DR STRING; 4097.A0A1S3XYB5; -.
DR PaxDb; 4097-A0A1S3XYB5; -.
DR GeneID; 107769963; -.
DR KEGG; nta:107769963; -.
DR OMA; MLFGLCK; -.
DR OrthoDB; 2882949at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004525; F:ribonuclease III activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0030422; P:siRNA processing; IBA:GO_Central.
DR CDD; cd00593; RIBOc; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR PANTHER; PTHR14950:SF66; RIBONUCLEASE 3-LIKE PROTEIN 2; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00535; RIBOc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR SUPFAM; SSF69065; RNase III domain-like; 1.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS50142; RNASE_3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 20..165
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 180..256
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 298..371
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
SQ SEQUENCE 375 AA; 41981 MW; CED9278591FFF018 CRC64;
MMTEANRLPA EEITNTATSV TAVEELLKYR FKNTKLLEEA LTHTSCNSSS ASNNYQRLAF
VGDAALGLAI SSYFFSVYPD VDCGKLTDLR AANVSTEKLA RVAVRHGLYN YLRRNSPILD
EKVKEFVITV QQEAEMEFYG GMMKAPKILA DIVESVMGAV YVDCGFDVNA FWVIFRGLLE
PIIMLNMLKE QPQPVTMLFG LCKKDGKQVE VEHRKEGDKN IASVYVDGQF VASASSEHKE
NAKLQVAKAA LKELFYDPYD EMDVEFVPSQ KKKTNVEFAP FQKIKMDVEF DPTKESEGAK
QKLNELCGRK KWSKPSYRIE KEIGPAHHRS FTCSVQVSIG ENVFSVTGDE KSRVKDAENS
AALAMIQGLQ ESEVS
//
