ID   A0A1S3YAK7_TOBAC        Unreviewed;       785 AA.
AC   A0A1S3YAK7;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Probable methyltransferase PMT28 {ECO:0000313|RefSeq:XP_016449048.1};
GN   Name=LOC107774095 {ECO:0000313|RefSeq:XP_016449048.1};
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016449048.1};
RN   [1] {ECO:0000313|Proteomes:UP000084051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX   PubMed=24807620; DOI=10.1038/ncomms4833;
RA   Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA   Goepfert S., Peitsch M.C., Ivanov N.V.;
RT   "The tobacco genome sequence and its comparison with those of tomato and
RT   potato.";
RL   Nat. Commun. 5:3833-3833(2014).
RN   [2] {ECO:0000313|RefSeq:XP_016449048.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000256|ARBA:ARBA00008361}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_016449048.1; XM_016593562.1.
DR   AlphaFoldDB; A0A1S3YAK7; -.
DR   STRING; 4097.A0A1S3YAK7; -.
DR   PaxDb; 4097-A0A1S3YAK7; -.
DR   GeneID; 107774095; -.
DR   KEGG; nta:107774095; -.
DR   OMA; YLMFPQN; -.
DR   OrthoDB; 1202783at2759; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR004159; Put_SAM_MeTrfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR10108:SF1102; METHYLTRANSFERASE PMT28-RELATED; 1.
DR   PANTHER; PTHR10108; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR   Pfam; PF03141; Methyltransf_29; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|RefSeq:XP_016449048.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW   Transferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|RefSeq:XP_016449048.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          72..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..115
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..160
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..219
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..271
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   785 AA;  89626 MW;  181341A317B80A5D CRC64;
     MRKQHTTLTR FGRKVRGSYQ SYGLGVKLAA VVILGLCFVF IWSVFSPSSY SITYQRENFD
     DIREPISAAN RKKVTSLVPS TKKSEPHKGH VVNKEDKKLK HRSSSGEKKK KLDGSLPSKS
     GSSWHKNEKS GVDRKRKGED LKLPKKVDEV KDQFLEGSET EELEKENEEE KIENKKQEEE
     KEVVKGKENV KEKSKNYKQE GEEEEVGNGK EKEETETNKE DEEGGGDDNE EREGNGELTN
     SEQLDQEVAE KVEDEDEKSR DTEKKMKKNL GPIFDPKAHY TWNFCSTRSK HNYIPCIDIE
     SVSGKLRNFR HHERSCPKAP QMCLVPLPPD GYETPVSWPE SKSKILYKNV AHPKLAAFVK
     TENWVVESGE YLTFPLNQSM PKGGIQHYLD FIEEMVPDIE WGKNIRVVLD IGCKDSSFSA
     SVLEKGVLTL TLGLKDDLVD LAQVALGRGF PAVVTPFGTR RLPFPSGVFD AIHCSDCRAS
     WHSNGGKHLI EMNRILRPGG YFILSSKHSS IEVEEAMSTL TASICWNILA DKTDEISDIR
     IKLYQKPHAN DMYQLRRKKV PPLCKANENP DASWYVPIKS CLHTIPESIE QRGTEWPEEW
     PKRLETFPDW MNNREKLIAD SEHWNAIVNN SYLVGLGIDW SNIRNVMDMK AINGGFAAAL
     AQQKVWVMNV IPVHAPNTLP IVFERGLVGA YHDWCEAFGT YPRSYDLLHA DHLFSRLKNR
     CKHPIVIVVE MDRILRPGGW AIIRDKVEIL DPLESILRSL HWEIRMTFAK DKEGILCAQK
     TMWRP
//