ID A0A1S3YB74_TOBAC Unreviewed; 821 AA.
AC A0A1S3YB74;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Structural maintenance of chromosomes protein 6A-like {ECO:0000313|RefSeq:XP_016449263.1};
GN Name=LOC107774285 {ECO:0000313|RefSeq:XP_016449263.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016449263.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016449263.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC6 subfamily.
CC {ECO:0000256|ARBA:ARBA00006793}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016449263.1; XM_016593777.1.
DR AlphaFoldDB; A0A1S3YB74; -.
DR SMR; A0A1S3YB74; -.
DR STRING; 4097.A0A1S3YB74; -.
DR PaxDb; 4097-A0A1S3YB74; -.
DR GeneID; 107774285; -.
DR KEGG; nta:107774285; -.
DR OMA; FMCHRSL; -.
DR OrthoDB; 78166at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0035861; C:site of double-strand break; IBA:GO_Central.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IBA:GO_Central.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR19306; STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6; 1.
DR PANTHER; PTHR19306:SF6; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 21..276
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 185..212
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 273..427
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 638..686
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 727..818
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 821 AA; 94223 MW; 0DD054901F9059DC CRC64;
MEDRVPATGM PKRLEAGIIS KIRLENFMCH SNLEIDFGDS VNFITGQNGS GKSAILTALC
VAFGSRARGT QRANTLKDFI KTGCSHALVH VEIKNRGEDA FKAETYGDLI IVERRISEST
GSIVLKNYQG KKVAAKREEL QELIVHFNID VENPCVIMSQ DKSREFLHSG NAKDKFKFFF
KATLLQQVED LLIGIQVQLK NANELVAELE KSISPIVKEL DELQVKIRNM EHIEEISHQV
DLLKKKLAWA WVYSVDRQLQ DKSKRIEELK GRIPTCQSRI DQHLRKMEEL NDQLAKKKAQ
IAHLMEKTSE VRRMTEELKH SLSSATKEKL ELEEEWRRRG NYIQKMAKRV KMLEQQIHDV
DEQNIRNTQA EEHDMEVKLE EFQAEVDKAN VVFQRLKNEE VTLIEKINQA KEQISNIVHE
IEENDKKDRD IRSRIRELQL HKSNKVTAFG GGRVMGLLEV IERHHRKFQR APIGPIGAHV
TLVDGDKWGI AIESAIGSLL NGFIVTDHKD SLLLRACARE ANYNNLQIII YEFSRPRLNI
PDHMLPRTHH PTAISVLRSD NPTVLNVLID VGNAERQVLV KDYDAGKAVA FEQRISNLKE
VYTSDGYKMF SRGSVQTILP PMKNVRSGHL SGSYDNLIKT LESEASEAQM KARQTRGMKR
SIDEELQGLQ DNLQSAKKRR HDAERVLRSK EFRLQDFKKS YLAESSSTAV STVDELHVEQ
SKIRDEIHER ENSLEELQVR LNEADTKAND VKISFENLCE SAKVEIGALE EAERELMMID
KDLKDAELKK NHYEDVMSKK VLSQLKGAEE EYQELEHNRR V
//
