ID A0A1S3YG82_TOBAC Unreviewed; 771 AA.
AC A0A1S3YG82;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Subtilisin-like protease SBT1.9 {ECO:0000313|RefSeq:XP_016451130.1};
GN Name=LOC107775853 {ECO:0000313|RefSeq:XP_016451130.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016451130.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016451130.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR RefSeq; XP_016451130.1; XM_016595644.1.
DR AlphaFoldDB; A0A1S3YG82; -.
DR SMR; A0A1S3YG82; -.
DR STRING; 4097.A0A1S3YG82; -.
DR PaxDb; 4097-A0A1S3YG82; -.
DR GeneID; 107775853; -.
DR KEGG; nta:107775853; -.
DR OMA; SIMICYR; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF631; SUBTILISIN-LIKE PROTEASE SBT1.9 ISOFORM X2; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..771
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010168366"
FT DOMAIN 29..115
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 138..584
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 660..763
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 147
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 218
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 545
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 771 AA; 83594 MW; 85AD0E0DA59628E2 CRC64;
METRLAPLMF SWFLLCLSLF LGISAQRSTY IVHLDKSFMP KIFASHQNWH SSIIDTIKID
VPTTPNNHHL TPKLLYSYDN VIHGFSAVLS KDELEALKKS PGFLSAYKDR TVEAHTTYTS
EFLKLNPASG LWPASGFGQD IIIGVLDSGI WPESASFRDD GLSEIPKKWK GICKPGKEFN
SSLCNRKLIG ANYFNKGLLA NNPSVNISMN SARDTDGHGT HVASIAAGSF AKGVSYFGYA
PGTARGIAPR ARIAVYKFSF EEGTFTSDLI AAMDQAVADG VDILTISYGW SNSPLYEDSI
AIASFGAMMK GVLVTASAGN NGPEMGTLNN GVPWIFTVAS CSTDRSFSGT LTLGNGFKIT
GFSLFPVRTM IKDFHLVNNG SLSTCDSSDP LSQVPNAERS IMICYSTAQE DLSVSDQMGA
ISESKFGAAI YVYEDPDVLS STFFPNPGVV VSSKEWKQVI DYATKSVKPK ASISFQETHI
DVKPAPVVSA FSSRGPSASY LRVAKPDIMA PGELILAAWP SNVSAAVIGV NTFLESDYRL
DSGTSMAAPH IAGIAAMLKG AHPEWSPSAI RSAMMTTANP LDNTDKPIKT PDYMVKRDAT
SLAMGAGLVD PNRAVDPGLI YDATPLDYVN LLCSMNLTVE QFKTIARSSA KHNCSNPSND
INYPSFIALF SPYGNYTWLE QKFKRTVTNV GAAAATYKVK VRAPKNSTIS ISPQTLVFEK
KYQKQDYSLT IRYKGVAEDQ AQSGSITWVE ENGHHTVRSP IVVAPEIDAW T
//
