ID A0A1S3YPS9_TOBAC Unreviewed; 616 AA.
AC A0A1S3YPS9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Serine/threonine-protein kinase EDR1-like isoform X2 {ECO:0000313|RefSeq:XP_016454128.1};
GN Name=LOC107778389 {ECO:0000313|RefSeq:XP_016454128.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016454128.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016454128.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016454128.1; XM_016598642.1.
DR AlphaFoldDB; A0A1S3YPS9; -.
DR GeneID; 107778389; -.
DR OrthoDB; 560089at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13999; STKc_MAP3K-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR23257:SF821; ATP BINDING PROTEIN; 1.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR Pfam; PF14381; EDR1; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_016454128.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 360..615
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 387
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 616 AA; 68682 MW; D3621BF5B912C27B CRC64;
MLKQLALTLV KGLRSTPAVV VKKIAGLVCD FYKHPKYKST HVSGTLEEVS HALGSQGIHM
LCQIKDGSCH SRAILFKVLA DTVGLECKLI VGFPRGGALE RTDSSKHICV TVILDSVELL
VDLMHYPGKL FPCSTKQRNR SHFFGESDSI ETDSYNSPMD PISPTCFSSD YSGTGSPEHP
LFRGPGRSIL GGRALSFKDC TYDVTSSRSA GASPLHTRRR RRRSISMIPE IGDDIVRVVR
EMNASMKKNH LSGGQATFDL STRKREDNSG NQVLNFHPDD LNTRNGEKGQ AQHFHGKCLA
SDKAISLPSS PHRTYGRGNA AGIFGSPDMM SRLEKVIESS RILNKPLLPF DEWNIDFSEI
TIGARVGIGF FGEVFRCIWN GTEVAVKVFL EQDLSEENIE DFANEISILS RIRHPNVILF
LGACTTPPRL SVITEFMEMG SLYHLIHVSG QKNNLSWQRR LKMLCDICRG LLCIHRMKIV
HRDLKSGNCL VNKHYKVKIC DFGLSRLLIS TPMQDSSSAG TPEWMAPELI RNEPFTEKCD
IFSFGVIIWE LYTLKKPWEG VPSIQVVYAV ANDGKRLEIP EGPLGKLISD CWAEPDERPS
CEEILSRLQE CRPSAS
//
