ID A0A1S3YPW5_TOBAC Unreviewed; 341 AA.
AC A0A1S3YPW5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Alkylated DNA repair protein alkB homolog 8-like isoform X1 {ECO:0000313|RefSeq:XP_016454259.1};
GN Name=LOC107778504 {ECO:0000313|RefSeq:XP_016454259.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016454259.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016454259.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the alkB family.
CC {ECO:0000256|ARBA:ARBA00007879}.
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DR RefSeq; XP_016454259.1; XM_016598773.1.
DR AlphaFoldDB; A0A1S3YPW5; -.
DR SMR; A0A1S3YPW5; -.
DR STRING; 4097.A0A1S3YPW5; -.
DR PaxDb; 4097-A0A1S3YPW5; -.
DR GeneID; 107778504; -.
DR KEGG; nta:107778504; -.
DR OMA; LHGRPCP; -.
DR OrthoDB; 147254at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0070988; P:demethylation; IEA:InterPro.
DR GO; GO:0019748; P:secondary metabolic process; IEA:UniProt.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032857; ALKBH4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12463:SF1; FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12463; OXYGENASE-RELATED; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 17..95
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 199..325
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 341 AA; 38311 MW; 1809B75F0A503D76 CRC64;
MGLPRFKRPG GTIESSSNLY VANCGPAVGL TFDTIEAVFG AYGPVKGVYL ADESGTRVIV
SYHEERSAES ALKALSRRAC PELGGRSLHI QYSVHSVCQV AVDDSIPVSM AASELDIPGL
YLIHDFISAE EEKELLAAVD TRPWQKLAKR RVQHYGYEFQ YSTRNVNANQ YLGELPSFLS
PILEKMSLFQ KLGYAETVLL DQLTVNEYPP GVGLSPHIDT HSAFEDLIFS LSLAGPCIME
FRKYSTGVWL TSPDTLNDEE AQNSEKSSKF LRRAIYLPPR SILLLSGEAR YVWHHYIPHH
KVDVVNDTRI RRASRRVSFT LRKVRKGPCE CEFPEYCDSQ K
//
