ID A0A1S3YQ08_TOBAC Unreviewed; 341 AA.
AC A0A1S3YQ08;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Programmed cell death protein 4-like {ECO:0000313|RefSeq:XP_016454137.1};
GN Name=LOC107778399 {ECO:0000313|RefSeq:XP_016454137.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016454137.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016454137.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDCD4 family.
CC {ECO:0000256|ARBA:ARBA00005497}.
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DR RefSeq; XP_016454137.1; XM_016598651.1.
DR AlphaFoldDB; A0A1S3YQ08; -.
DR SMR; A0A1S3YQ08; -.
DR STRING; 4097.A0A1S3YQ08; -.
DR PaxDb; 4097-A0A1S3YQ08; -.
DR GeneID; 107778399; -.
DR KEGG; nta:107778399; -.
DR OMA; GMEQGFI; -.
DR OrthoDB; 1217702at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR039778; PDCD4.
DR PANTHER; PTHR12626; PROGRAMMED CELL DEATH 4; 1.
DR PANTHER; PTHR12626:SF8; PROGRAMMED CELL DEATH PROTEIN 4-LIKE; 1.
DR Pfam; PF02847; MA3; 2.
DR SMART; SM00544; MA3; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS51366; MI; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 131..252
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 295..341
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 341
FT /evidence="ECO:0000313|RefSeq:XP_016454137.1"
SQ SEQUENCE 341 AA; 37632 MW; 1B9AC4900E12FA2D CRC64;
MASGEGFLTK EQREMLNVAP PNVEVLSSSP KSPTLKSPGT KSSSVLLSEH HVKAPGGGRA
STAGIAVRHV RRTHSGKHIR VKKDGAGGKG TWGKLLDTEG ESHLDRNDPN YDSGEEPYEL
VGTAVSDPLD DYKKSVVSII EEYFSTGNVE QAASDLKELG STEYHPYFIK RLVSLAMDRH
DKEKEMTSVL LSALYADVIS PTQISKGFYM LLESADDLSV DIPDTVNILA LFIARAVVDD
ILPPAFIARV RKMLPKSSKG FQVLQTAEKS YLSAPHHAEL VERRWGGSTQ FTVEEVKKRI
AELLREYVES GDTVEACRCI RQLEVSFFYH EVVKRALVLA M
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