ID A0A1S3YQ70_TOBAC Unreviewed; 970 AA.
AC A0A1S3YQ70;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=GPI ethanolamine phosphate transferase 3 {ECO:0000256|ARBA:ARBA00020841};
GN Name=LOC107778455 {ECO:0000313|RefSeq:XP_016454197.1,
GN ECO:0000313|RefSeq:XP_016454198.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016454197.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016454197.1, ECO:0000313|RefSeq:XP_016454198.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
CC {ECO:0000256|ARBA:ARBA00008695}.
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DR RefSeq; XP_016454197.1; XM_016598711.1.
DR RefSeq; XP_016454198.1; XM_016598712.1.
DR STRING; 4097.A0A1S3YQ70; -.
DR PaxDb; 4097-A0A1S3YQ70; -.
DR GeneID; 107778455; -.
DR KEGG; nta:107778455; -.
DR OrthoDB; 5479199at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IBA:GO_Central.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IBA:GO_Central.
DR CDD; cd16023; GPI_EPT_3; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR037675; PIG-O_N.
DR InterPro; IPR039524; PIGO/GPI13.
DR PANTHER; PTHR23071:SF1; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3; 1.
DR PANTHER; PTHR23071; PHOSPHATIDYLINOSITOL GLYCAN; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transferase {ECO:0000256|ARBA:ARBA00022679,
KW ECO:0000313|RefSeq:XP_016454197.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 551..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 604..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 684..703
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 723..745
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 864..891
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 903..928
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 948..969
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 970 AA; 108427 MW; 04FA67D962DD3B78 CRC64;
MSKSGAASWV WWKSENLGKR RWVFMVFLGI LILHGLAILV FTRGFLLTRT ELSQYSHCSE
IQQSPCFSPP QDDKMVNHSK GCWTKPAVGR LVILVLDALR YDFVAPSTFF EEKKPWMDRL
QVLHKLASRP GSSAKIFKAI ADPPTTSLQR LKGLTTGGLP TFVDVGNSFG APAIAEDNLI
YQMAKNGKRV VMMGDDTWVQ LFPHHFNISH PFPSFNVKDL DTVDNGCIEH LFPYLYKEDW
DVLIAHFLGV DHAGHIFGVD STEMIEKLDQ YNGILEKVVD VLESQSGPGG LHENTLLLVM
GDHGQTINGD HGGGAPEEVE TSLFALSLQK HPSSLPSETD SSSCRLDMEK RTICTSSIEQ
LDFAATVSAL LGIPYPFGSI GRVNPELYAL AAGTWNLDIF TSKSGLNLSS LERWMQNYVN
ALCINTWQVK RYIDVYSASS VIGFSDKDLL HVSNLYAQAH DIWLHTKEAL LKCKSEHCFT
SLPQLKKQVE AYSNFLSSIA ALARSKWTEF NLKMMGTGFC ILVLSLFVHI FTIKKLDKLC
SFHLPHGGNF VISFESIFAY AAVLIRAFSF LSNSFILEEG KVASFLLATA GMLQLRHAIV
KKKMLLEGLL FVLVVPLLRF GIELGQSKQA VNSLFLKSFP SWTIGIDEAT NLWIYVADFL
SFLALTILAY ILYKSISYSS CQGIFKYVVV GSIFTSSLIA LAWAFDGDLF SPSTMIVDIK
AYWIPRIIYV FGLLQLLLLT ISQLCGKEKT SGWEEDTIVK ATAMLSAWSS TIIILSGKQG
PLIALAAVIQ EFHFTGWCII RLILLEPRAK NDCTGSSISY SSPVTKWSLL AVCLFFCTGH
WCAFDGLRYA AAFVGFDEFN LFRQAVLLTI DTFGFSHILP VMGLPLLVAF LRPEVQAEKR
KQLFFFQLCQ VYLTYGLILA TTMTLTIICV TIQRRHLMVW GLFAPKFVFD AVGLLLTDFF
ICFASLYYFA
//
