ID A0A1S3YYA2_TOBAC Unreviewed; 766 AA.
AC A0A1S3YYA2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Subtilisin-like protease SBT1.9 {ECO:0000313|RefSeq:XP_016456822.1};
GN Name=LOC107780755 {ECO:0000313|RefSeq:XP_016456822.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016456822.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016456822.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR RefSeq; XP_016456822.1; XM_016601336.1.
DR AlphaFoldDB; A0A1S3YYA2; -.
DR SMR; A0A1S3YYA2; -.
DR STRING; 4097.A0A1S3YYA2; -.
DR PaxDb; 4097-A0A1S3YYA2; -.
DR GeneID; 107780755; -.
DR KEGG; nta:107780755; -.
DR OMA; SYECSAN; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF545; SUBTILISIN-LIKE PROTEASE SBT3; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..766
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010373729"
FT DOMAIN 30..114
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 139..580
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 655..757
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 148
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 219
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 542
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 766 AA; 82724 MW; FC8362DCBAEEE831 CRC64;
MGLPYFHLLF LSWFLSALVF CLLATAQRST YIVHLDKSLM PNIFADHHHW HSSTIDSIKA
AVPSSVDRFH SAPKLVYSYD NVFHGFSAVL SKDELQALKK SPGFVSAYKD RTVEPQTTHT
SDFLKLNPSS GLWPASGLGQ DVIIGVLDSG IWPESASFRD DGMPEIPKRW KGICKPGTQF
NTSLCNRKLI GANYFNKGIL ANDPTVNISM NSARDTDGHG THVASIAAGN FAKGVSHFGY
APGTARGVAP RARLAVYKFS FNEGTFTSDL IAAMDQAVAD GVDMISISFG FRFIPLYEDS
ISIASFGAMM KGVLVSASAG NRGPGIGSLN NGSPWILCVA SGHTDRTFAG TLTLGNGLKI
RGWSLFPARA IVKDSTVIYN KTLADCNSEE LLSQLSDPER TIIICEDNGD FSDQMRIVAR
ARLKAGIFIS EDPGVFRSAT FPNPGVVINK KEGKQAINYV KNTVDPTATI TFQETYLDVK
PAPVVAASSA RGPSRSYLGI AKPDILAPGV LILAAYPPNV FATSIGPNIE LSTDYILESG
TSMAAPHAAG IAAMLKGAHP EWSPSAIRSA MMTTADPLDN TRKPIKDSDI NKAATPLDMG
AGHVDPNRAL DPGLVYDATP QDYLNLLCSL NFTEEQFKTI ARSSDNHNCS NPSADLNYPS
FIALYPLEGP FTLLEQKFRR TVTNVGKGAA TYKAKIKAPK NTTVSVSPQT LMFKKKNEKQ
SYTLTIRYLG DEGQSRNVGS ITWVEENGSH SVRSPIVTSP IIEISS
//
