ID A0A1S3Z0Z3_TOBAC Unreviewed; 418 AA.
AC A0A1S3Z0Z3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Equilibrative nucleotide transporter 3-like isoform X1 {ECO:0000313|RefSeq:XP_016457801.1, ECO:0000313|RefSeq:XP_016457802.1};
GN Name=LOC107781585 {ECO:0000313|RefSeq:XP_016457801.1,
GN ECO:0000313|RefSeq:XP_016457802.1, ECO:0000313|RefSeq:XP_016457803.1,
GN ECO:0000313|RefSeq:XP_016457804.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016457802.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016457801.1, ECO:0000313|RefSeq:XP_016457802.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016457801.1; XM_016602315.1.
DR RefSeq; XP_016457802.1; XM_016602316.1.
DR RefSeq; XP_016457803.1; XM_016602317.1.
DR RefSeq; XP_016457804.1; XM_016602318.1.
DR STRING; 4097.A0A1S3Z0Z3; -.
DR PaxDb; 4097-A0A1S3Z0Z3; -.
DR GeneID; 107781585; -.
DR KEGG; nta:107781585; -.
DR OMA; FNIMDWV; -.
DR OrthoDB; 239997at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IBA:GO_Central.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF30; EQUILIBRATIVE NUCLEOTIDE TRANSPORTER 2; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 418 AA; 45987 MW; 80824204E5A4D306 CRC64;
MAEDNRVPVK LEGKYAAMLV CWLLGNGCLF SWNSMLTIED YYVYLFPDYH PSRVLTLIYQ
PFALGTLAIL AYNEAKMNTR KRNLFGYSLF FISTLLVLVL DLATSGKGGL GTFIGICAIS
GAFGVADAHV QGGMIGDLAY MLPEFIQSFL AGLAASGVLT SALRLITKAA FENSKDGLRN
GAILFFSVST FFELLCVLLY AFVFPKLPIV KYYRAKAASE GSKTVAGDLA AGGVFKHEGS
ETKSKHGPEH VERLNNKQLL LQNIDYAIDL FLIYALTLSI FPGFLSEDTG SHSLGSWYAL
VLIAMYNVWD LIGRYVPLIK CLKLESRKGL MLVILLRFLL IPAFYFTAKY GDQGWMIMLT
SFLGLSNGYL TVCVLTSAPK GYKGPEQNAL GNLLVLFLLG GIFAGVTLDW LWLIGKGW
//
