ID A0A1S3Z858_TOBAC Unreviewed; 453 AA.
AC A0A1S3Z858;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Apyrase-like {ECO:0000313|RefSeq:XP_016460392.1};
GN Name=LOC107783879 {ECO:0000313|RefSeq:XP_016460392.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016460392.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016460392.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_016460392.1; XM_016604906.1.
DR AlphaFoldDB; A0A1S3Z858; -.
DR SMR; A0A1S3Z858; -.
DR STRING; 4097.A0A1S3Z858; -.
DR PaxDb; 4097-A0A1S3Z858; -.
DR GeneID; 107783879; -.
DR KEGG; nta:107783879; -.
DR OMA; HFANAPQ; -.
DR OrthoDB; 180318at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IBA:GO_Central.
DR GO; GO:0009134; P:nucleoside diphosphate catabolic process; IBA:GO_Central.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF87; APYRASE; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
DR PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Hydrolase {ECO:0000256|RuleBase:RU003833};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..453
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010284735"
FT ACT_SITE 169
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 199..203
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 453 AA; 49634 MW; 08D52736464ACCB5 CRC64;
MLNKKSHFVF TFLAILLLLP LSFFSSTNAH KPLRRHLLSH ESENYAVIFD AGSTGSRVHV
FRFNENLELL PIGNDIEFFM ATKPGLSSYA DDPKAAANSL EPLLEGAEGA VPKELQSETP
LELGATAGLR MLKGDAAEKI LQAVRDLVKN ESTFHTKDQW VSILDGTQEG SYMWVAINYL
LGNLGKNYKS TTATIDLGGG SVQMAYAISK EHFANAPQNE DGEPYVQEKH LLANDYYLYV
HSYLNYGQLA GRAEIFKASR NYSNPCALEG YDGYYSYGGV NYKVKAPSSG TSLKKCRALT
RKALKISAPC NYKNCTFNGV WNGGGGAGSK TVHASSFFYD IGAQVGIVDS KFPSAIAKPI
QYLNAAKVAC KTKAADIKSV FPNAQDRDIP YLCIDLVYDY TLLVDGLGLN PYKDITVMHD
VKYKNYLVGA AWPLGCAIDL VSSSPKKTRI SSH
//
