ID A0A1S3Z9Y7_TOBAC Unreviewed; 721 AA.
AC A0A1S3Z9Y7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Monosaccharide-sensing protein 2-like {ECO:0000313|RefSeq:XP_016461192.1, ECO:0000313|RefSeq:XP_016461193.1};
GN Name=LOC107784560 {ECO:0000313|RefSeq:XP_016461192.1,
GN ECO:0000313|RefSeq:XP_016461193.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016461193.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016461192.1, ECO:0000313|RefSeq:XP_016461193.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_016461192.1; XM_016605706.1.
DR RefSeq; XP_016461193.1; XM_016605707.1.
DR STRING; 4097.A0A1S3Z9Y7; -.
DR PaxDb; 4097-A0A1S3Z9Y7; -.
DR GeneID; 107784560; -.
DR KEGG; nta:107784560; -.
DR OMA; HEKMPEM; -.
DR OrthoDB; 457140at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR48020; PROTON MYO-INOSITOL COTRANSPORTER; 1.
DR PANTHER; PTHR48020:SF53; SUGAR TRANSPORTER; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 2.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 606..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..700
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 330..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 721 AA; 77781 MW; 0AB22E7781A0B35A CRC64;
MSGAVLIALA AAIGNLLQGW DNATIAGSVL YIKKEFNLQT QPTMEGLIVA MSLIGATVIT
TFSGPVSDML GRRPMLIISS VLYFLSGLVM LWSPNVYVLL LARLLDGFGI GLAVTLVPVY
ISETAPPEIR GQLNTFPQFT GCVGMFLSYC MVFGMSLTPS PSWRLMLGVL SIPSLAYFFF
TLFYLPESPR WLVSKGRMKE AKQVLQRLRG REDVSGEMAL LIEGLGVGGE VSIEEYIIGP
DSELVDNQDE KDQIKLYGAE EGLSWIAKPV TGQSTLGLAS RHGSMANQSM LMDPLVTLFG
SVHEKLPEMG SMRSMLFSNV GSMFNITENQ EKHEQWDEES QKDDEHHMSD GSGAESDDNL
RSPLLSRQGT NAETNMGPPT SLSMRQGSNL VHANGEQASM GIGGGWQLAY RKDEKKEGAL
KRIYLHEEGG AGSRRGSIIS LPGDAHAEGE FIHAAALVSQ SVLRAESLLG QQSIEEAVET
QSDAVTKRPG WKALFEPGVK HALIVGVGIQ ILQQFSGING VLYYTPQILE QAGVGILLSN
LGIGSDSASL LISAVTTLLM LPSIVVAMRL MDFAGRRWLL LATLPVLLAS LIVLVIGNVI
SMGAVMHAVI STISVVVYFC TFVMGFGPIP NILCSEIFPT SVRGICIAIC ALTFWFGDII
VTYSLPVMLT SIGLGGVFGI YAVVCALAWV FVYLKVPETK GMPLEVITEF FAVGAKQAAR
E
//
