ID A0A1S3ZDJ3_TOBAC Unreviewed; 462 AA.
AC A0A1S3ZDJ3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Probable protein phosphatase 2C 28 isoform X2 {ECO:0000313|RefSeq:XP_016462520.1};
GN Name=LOC107785680 {ECO:0000313|RefSeq:XP_016462520.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016462520.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016462520.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_016462520.1; XM_016607034.1.
DR AlphaFoldDB; A0A1S3ZDJ3; -.
DR GeneID; 107785680; -.
DR OrthoDB; 11028at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd06222; RNase_H_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR47992:SF20; PROTEIN PHOSPHATASE 2C 28-RELATED; 1.
DR Pfam; PF00481; PP2C; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 248..462
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 184..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..235
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 51509 MW; 9282FA77CAB6CEC4 CRC64;
MKPSKSFQAL EWEDIYTLCF WHIWLNRNNN NINNISNDIS VKMTLSKAAE FKYLTGNKHS
SLNTINFSIR WQKPSMGSFK LNCDSAYINN TNVGGLGGVI RNSHGKWMVG FQKLTNVISN
THAELLALET GLRVVVQFKL HPLEIEMDST KRGKSGDPDI IKIKRTSTPD DVASVLLKER
ERQGVYGAGR EVNSTAEQEE EDAENEDYDG DDTGAKDEDN GEVVDDPEED GGDAEVSDGD
QKQQRRVSYG FHLVEGKMKH GMEDYLVAEN RKMDGHNLGL YAIFDGHSGR EVAEYLQSHL
FDNILSEPDF WKNPVTAFKK AYRDTDGDIL ENVVGARGGS TAVTAILIDQ KLLVVANVGD
SRAVLIQRGK VKQITVDHEP EKKEERDLVE SKGGFVIKMP GNVPRVDGQL AMTRAFGDAK
LKDHITVEPN VTIEKIDKDT DFIILASDGL WKVIYSATGN VE
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