ID A0A1S3ZJ55_TOBAC Unreviewed; 616 AA.
AC A0A1S3ZJ55;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
GN Name=LOC107787389 {ECO:0000313|RefSeq:XP_016464434.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016464434.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016464434.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR RefSeq; XP_016464434.1; XM_016608948.1.
DR AlphaFoldDB; A0A1S3ZJ55; -.
DR SMR; A0A1S3ZJ55; -.
DR STRING; 4097.A0A1S3ZJ55; -.
DR PaxDb; 4097-A0A1S3ZJ55; -.
DR GeneID; 107787389; -.
DR KEGG; nta:107787389; -.
DR OrthoDB; 169924at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR PANTHER; PTHR10233:SF16; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA-LIKE ISOFORM X1; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|RefSeq:XP_016464434.1};
KW Protein biosynthesis {ECO:0000313|RefSeq:XP_016464434.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 67991 MW; B7F32DFFD273A203 CRC64;
MDPRRPSRVI DPKVRRVGFF APDPHTSDPD NHPGLSSSPP GNSVIPHAFE SVSQAVPVPN
STSTSRPRRS SFDESEQLVV GSYNPMQSVL GTSPTSSGIG VEGEFSEDST HWIRQTDGFS
LTSAARLTES KDDQEQISAQ VAETSNEVER NGKPLKGKST KAERRALQEA QRAAKATGKG
GETSGTKLRG QSGKPTKQPS QKKDSGPMIS SVATHETKGG DRPLEKDRKK DVPAPRMQFD
DKNRVEKAKK RAVVKKTEAR NRVELFRHLP QYEQGTQLPD LESRFFHLDP MHPAVYKVGL
QYLAGDVVGG NARCVAMLQA FQQAIKDYST PREKALGRDL TARINGYVSF FNECRPLSIS
MGNAIRFLKA RIAKLSLTLS EAEAKAALYS DIERFINEKI ILADRVITRQ AVTKIRDGDV
LLTYGSSSVV EMILLHAYEL GKRFRVIVVD SRPKLEGKAL LRRLVKGGLC CTYTHINAVS
YIMHEVTRVF MGAASVLSNG TVYSRIGTAC VAMVAHAFRV PLLICCEAYK FHERVQLDSV
CSNELGEPDA ISKVPGRLDV NSSDNWISKD NIQLLNLMYD VTPSDCVSMI ITDYGMIPTT
SVPVIVREYG REHLLI
//
