ID A0A1S3ZJA6_TOBAC Unreviewed; 487 AA.
AC A0A1S3ZJA6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
GN Name=LOC107787429 {ECO:0000313|RefSeq:XP_016464484.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|Proteomes:UP000084051, ECO:0000313|RefSeq:XP_016464484.1};
RN [1] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [2] {ECO:0000313|RefSeq:XP_016464484.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Phe-tRNA synthetase alpha subunit type 2 subfamily.
CC {ECO:0000256|ARBA:ARBA00006703}.
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DR RefSeq; XP_016464484.1; XM_016608998.1.
DR AlphaFoldDB; A0A1S3ZJA6; -.
DR SMR; A0A1S3ZJA6; -.
DR STRING; 4097.A0A1S3ZJA6; -.
DR PaxDb; 4097-A0A1S3ZJA6; -.
DR GeneID; 107787429; -.
DR KEGG; nta:107787429; -.
DR OMA; QIEGWVM; -.
DR OrthoDB; 4619at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0009328; C:phenylalanine-tRNA ligase complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IBA:GO_Central.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IBA:GO_Central.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR Gene3D; 1.10.10.2320; -; 1.
DR Gene3D; 1.10.10.2330; -; 1.
DR Gene3D; 3.30.1370.240; -; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004529; Phe-tRNA-synth_IIc_asu.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR InterPro; IPR040724; PheRS_DBD1.
DR InterPro; IPR040725; PheRS_DBD3.
DR NCBIfam; TIGR00468; pheS; 1.
DR PANTHER; PTHR11538:SF40; PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF18552; PheRS_DBD1; 1.
DR Pfam; PF18553; PheRS_DBD3; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000313|RefSeq:XP_016464484.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051}.
FT DOMAIN 220..470
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 487 AA; 56323 MW; 922EFF237A832E99 CRC64;
MAEDAILEFL EKNEEISDSF KFAEQHGFLH EEIVNVIRSL NGFRFVDAQD IRRERWVLTE
EGKTYASVGS PEFQLFSAVP PEGIAREELQ KKLDPAVYKI GCQQAIKNKW VEMAKTQVSR
KVHHADDKVK DSLLRIQNGE AVNQEDIDAL KRRKLISQQV WKGNSVRKGP NYAPKRKRAA
TDLTRENLQR GDWKELEFKE YNFSAKGQPV EGGHLHPLLK VRRQIQMIFL NMGFEEMPTN
NYVESSFWNF DALFQPQQHP ARDSHDTFFL KVPSTTKMLP EEYVERVKQV HESGGYQSRG
YGYDWKREEA NKNLLRTHTT AVSSRMLCAL AQKPFAPKKY YSIDRVFRNE AVDRTHLAEF
HQIEGLICDR GLTLGDLIGV LHDFFARLGM SKLRFKPAYN PYTEPSMEIF SYHEGLKKWV
EVGNSGMFRP EMLLPMGLPE DVRVIAWGLS LERPTMILYG IDNIRDLFGP KVDIGLIKRN
PICRLGL
//
